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SR-AI/MSR Antibody

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-1560
    • Availability
      Product Discontinued

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SR-AI/MSR Antibody Summary

Immunogen
Synthetic peptide corresponding to aa 325-342 of human MSR1. MSR1 is also known as scavenger receptor A.
Epitope
aa 325-342
Specificity
Recognizes the 75 kDa membrane glycoprotein human macrophage scavenger receptor (MSR) type 1. MSR1 has been shown to be expressed on microglia and mato cells of the brain but not astrocytes or neurons.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
MSR1
Purity
Unpurified
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Applications/Dilutions

Dilutions
  • ELISA 1:50000-1:100000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:200
  • Western Blot 1:2000
Application Notes
For Immunoprecipitation, protein digestion and antigen retrieval are not required. *Optimal dilutions should be determined by the end user.

Reactivity Notes

Reacts with Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
0.09% Sodium Azide
Purity
Unpurified

Alternate Names for SR-AI/MSR Antibody

  • CD204 antigen
  • CD204
  • Macrophage acetylated LDL receptor I and II
  • macrophage scavenger receptor 1
  • macrophage scavenger receptor type III
  • MSR1
  • phSR1
  • phSR2
  • SCARA1
  • SCARA1macrophage scavenger receptor types I and II
  • Scavenger receptor class A member 1
  • scavenger receptor class A, member 1
  • SR-A
  • SRAI
  • SR-AI

Background

Macrophage scavenger receptors (MSR) are membrane glycoproteins that mediate the recognition and uptake of a variety of macromolecules, including modified lipoproteins, advanced glycation end (AGEs) products and amyloid b-protein (Abeta). While the normal role of MSR is associated with cell adhesion and host defense mechanisms, it also has been implicated in the development of atherosclerosis and Abeta deposition in Alzheimer's disease (AD).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NB100-1560
SR-AI/MSR Antibody
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Bioinformatics

Gene Symbol MSR1
Entrez
Uniprot