SP-B/Surfactant Protein B Antibody (RM370)

Western Blot: SP-B/Surfactant Protein B Antibody (RM370) [NBP2-77431] - Western Blot of human lung tissue lysate using NBP2-77431.

Immunohistochemistry: SP-B/Surfactant Protein B Antibody (RM370) [NBP2-77431] - Immunohistochemical staining of formalin fixed and paraffin embedded human lung cancer tissue section using NBP2-77431.

• Reactivity: Hu
• Applications: WB, IHC
• Clone: RM370
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

SP-B/Surfactant Protein B Antibody (RM370) Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: A peptide corresponding to residues near C-terminus of human SP-B/Surfactant Protein B
• Specificity: This antibody reacts to human SP-B/Surfactant Protein B and proSP-B
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: SFTPB
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:500-1:1000
  • Western Blot 1:500 - 1:1000

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 50% Glycerol/PBS, 1% BSA
• Preservative: 0.09% Sodium Azide
• Purity: Protein A purified

Alternate Names for SP-B/Surfactant Protein B Antibody (RM370)

• 18 kDa pulmonary-surfactant protein
• 6 kDa protein
• PSP-B
• pulmonary surfactant-associated protein B
• Pulmonary surfactant-associated proteolipid SPL(Phe)
• SFTB3
• SFTP3
• SFTPB
• SMDP1
• SP-B surfactant, pulmonary-associated protein B
• SP-B
• surfactant protein B

Background

The SFTPB gene encodes the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Surfactant is composed of phospholipids and other surfactant-associated proteins (Clark et al., 1995 [PubMed 7644495]). See also SFTPA1 (MIM 178630), SFTPC (MIM 178620), and SFTPD (MIM 178635).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SFTPB