Somatostatin R5/SSTR5 Antibody - BSA Free

Western Blot: Somatostatin R5/SSTR5 Antibody [NB100-56498] - Analysis of Somatostatin R5/SSTR5 in human pancreas lysate in the 1) absence and 2) presence of immunizing peptide using Somatostatin Receptor 5 antibody at 0.25 ug/ml.

Analysis of a FFPE tissue section of human placenta using 1:200 dilution of Somatostatin R5/SSTR5 antibody (NB100-56498). The staining was developed using HRP labeled anti-rabbit secondary antibody and DAB reagent, and nuclei of cells were counter-stained with hematoxylin.

• Reactivity: Hu, Pm
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

Somatostatin R5/SSTR5 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Somatostatin R5/SSTR5 Antibody - BSA Free (NB100-56498) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A portion of amino acids 300-350 of human SSTR5 was used as the immunogen.
• Predicted Species: Primate (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SSTR5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100 - 1:500
  • Immunohistochemistry-Paraffin 1:100 - 1:500
  • Western Blot 0.5 - 2.0 ug/ml
• Application Notes: The expected size of SSRT5, based on amino acid content, is approximately 40 kD. It is believed that the 5-10 kD increase in observed size is due to glycosylation.
• Control:

  Human Pancreas Whole Tissue Lysate (Adult Whole Normal)

Reactivity Notes

The Somatostatin Receptor 5 amino acid sequence used as immunogen for this antibody is 94% in chimpanzee.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Somatostatin R5/SSTR5 Antibody - BSA Free

• Somatostatin R5
• somatostatin receptor 5
• somatostatin receptor subtype 5
• somatostatin receptor type 5
• SomatostatinR5
• SS5R
• SS-5-R
• SS5-R
• SST5
• SSTR5

Background

Somatostatin is a multifunctional protein affecting exocrine and endocrine protein secretion, neurotransmission, and neuronal modulation and regulating cell proliferation. All these functions of Somatostatin are executed through a class of GPCR protein family members called somatostatin receptor. Till date, 6 classes of somatostatin receptors have been discovered out of which SSTR5, 364A.A protein, is a receptor subtype expressed predominantly in the pituitary and hypothalamus region of brain. Studies revealed that SSTR5 contains seven transmembrane regions and undergoes homodimerization and also heterodimerizes with SSTR1. Although the specific functions of SSTR5 are still elusive, the studies indicate that it complements SSTR2 regulation of ACTH secretion. Polymorphisms in SSTR5 gene have been observed in patients with acromegaly.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SSTR5
• Uniprot:
  • P35346(Human)