Somatostatin R5/SSTR5 Antibody

Images

 
Western Blot: Somatostatin R5/SSTR5 Antibody [NB100-56498] - Analysis of Somatostatin R5/SSTR5 in human pancreas lysate in the 1) absence and 2) presence of immunizing peptide using Somatostatin Receptor 5 antibody at ...read more
Immunohistochemistry-Paraffin: Somatostatin R5/SSTR5 Antibody [NB100-56498] - Analysis of human placenta using Somatostatin Receptor 5 antibody at 10 ug/ml.

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Somatostatin R5/SSTR5 Antibody Summary

Immunogen
A portion of amino acids 300-350 of human SSTR5 was used as the immunogen.
Specificity
The Somatostatin Receptor 5 amino acid sequence used as immunogen for this antibody is 100% homologous in human and 94% in chimp. The expected size of SSRT5, based on amino acid content, is approximately 40 kD. It is believed that the 5-10 kD increase in observed size is due to glycosylation.
Predicted Species
Primate (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SSTR5
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 0.25 ug/ml
  • Immunohistochemistry 10 ug/ml
  • Immunohistochemistry-Paraffin 10 ug/ml
Control
Human Pancreas Whole Tissue Lysate (Adult Whole Normal)

Reactivity Notes

Reacts with Human. Predicted to react with Chimpanzee.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.2% gelatin
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Somatostatin R5/SSTR5 Antibody

  • Somatostatin R5
  • somatostatin receptor 5
  • somatostatin receptor subtype 5
  • somatostatin receptor type 5
  • SomatostatinR5
  • SS5R
  • SS-5-R
  • SS5-R
  • SST5
  • SSTR5

Background

Official Gene Symbol: SSTR5 Gen Bank Accession Number: NP_001044 Gene ID: 6755 (human) Gene Map Locus: 16p13.3 (human) Somatostatin is a multifunctional protein affecting exocrine and endocrine protein secretion, neurotransmission, and neuronal modulation and regulating cell proliferation. All these functions of Somatostatin are executed through a class of GPCR protein family members called somatostatin receptor. Till date, 6 classes of somatostatin receptors have been discovered out of which SSTR5, 364A.A protein, is a receptor subtype expressed predominantly in the pituitary and hypothalamus region of brain. Studies revealed that SSTR5 contains seven transmembrane regions and undergoes homodimerization and also heterodimerizes with SSTR1. Although the specific functions of SSTR5 are still elusive, the studies indicate that it complements SSTR2 regulation of ACTH secretion. Polymorphisms in SSTR5 gene have been observed in patients with acromegaly.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NB100-56498AF350
Alexa Fluor 405 NB100-56498AF405
Alexa Fluor 488 NB100-56498AF488
Alexa Fluor 532 NB100-56498AF532
Alexa Fluor 594 NB100-56498AF594
Alexa Fluor 647 NB100-56498AF647
Alexa Fluor 700 NB100-56498AF700
Alexa Fluor 750 NB100-56498AF750
Biotin NB100-56498B
DyLight 350 NB100-56498UV
DyLight 405 NB100-56498V
DyLight 488 NB100-56498G
DyLight 550 NB100-56498R
DyLight 594 NB100-56498DL594
DyLight 650 NB100-56498C
DyLight 680 NB100-56498FR
DyLight 755 NB100-56498IR
FITC NB100-56498F
HRP NB100-56498H
Janelia Fluor 549 NB100-56498JF549
Janelia Fluor 646 NB100-56498JF646

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Bioinformatics

Gene Symbol SSTR5
Uniprot
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