SMNDC1 Antibody (PCRP-SMNDC1-1A9)

Immunocytochemistry/Immunofluorescence: SMNDC1 Antibody (PCRP-SMNDC1-1A9) [NBP3-07233] - Immunofluorescence Analysis of PFA-fixed HeLa cells using SMNDC1 Mouse Monoclonal Antibody (PCRP-SMNDC1-1A9) followed by goat anti- Mouse IgG-CF488 (green). CF640A phalloidin (red).

Flow Cytometry: SMNDC1 Antibody (PCRP-SMNDC1-1A9) [NBP3-07233] - Flow Cytometric Analysis of PFA-fixed HeLa cells. SMNDC1 Mouse Monoclonal Antibody (PCRP-SMNDC1-1A9) followed by goat anti- Mouse IgG-CF488 (blue); unstained cells (red).

Protein Array: SMNDC1 Antibody (PCRP-SMNDC1-1A9) [NBP3-07233] - Analysis of Protein Array containing more than 19,000 full-length human proteins using SMNDC1 Mouse Monoclonal Antibody (PCRP-SMNDC1-1A9).

• Reactivity: Hu
• Applications: Flow, ICC/IF, MA
• Clone: PCRP-SMNDC1-1A9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

SMNDC1 Antibody (PCRP-SMNDC1-1A9) Summary

• Description: 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-08232)
  
  Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.
• Immunogen: Recombinant full-length human SMNDC1 protein (Uniprot: O75940 )
• Localization: Nucleus. Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: SMNDC1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1-2 ug/million cells
  • Immunocytochemistry/ Immunofluorescence 1-2 ug/ml
  • Protein Array
• Application Notes: Optimal dilution for a specific application should be determined.
• Theoretical MW: 30 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 10 mM PBS with 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein A or G purified

Alternate Names for SMNDC1 Antibody (PCRP-SMNDC1-1A9)

• SMNRSMN-related protein
• SPF30splicing factor 30, survival of motor neuron-related
• survival motor neuron domain containing 1,30 kDa splicing factor SMNrp
• Survival motor neuron domain-containing protein 1
• survival of motor neuron-related-splicing factor 30

Background

SMNDC1 is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SMNDC1
• Uniprot:
  • O75940(Human)