SMCX Antibody

ELISA: SMCX Antibody [22270002] - Affinity Purified

Product Discontinued

SMCX Antibody Summary

• Immunogen: This antibody is specific for the C Terminus Region of the target protein (NM_004187).
• Specificity: This product is specific for Human JARID1C.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KDM5C
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:5000-1:20000
• Application Notes: This antibody is useful in ELISA and Western Blot.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for SMCX Antibody

• DXS1272E
• DXS1272EMRXJ
• EC 1.14.11
• EC 1.14.11.-
• Histone demethylase JARID1C
• JARID1C
• JARID1Clysine-specific demethylase 5C
• Jumonji, AT rich interactive domain 1C (RBP2-like)
• jumonji, AT rich interactive domain 1C
• Jumonji/ARID domain-containing protein 1C
• KDM5C
• lysine (K)-specific demethylase 5C
• MRXSJ
• Protein SmcX
• Protein Xe169
• Smcx homolog, X chromosome
• SMCX
• SMCXselected cDNA on X
• Smcy homolog, X-linked (mouse)
• Smcy homolog, X-linked
• XE169
• XE169JmjC domain-containing protein SMCX

Background

This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SMCX Antibody (22270002)(2)

Publications using 22270002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Bioinformatics

• Gene Symbol: KDM5C
• Entrez:
  • 8242(Human)
• Uniprot:
  • P41229(Human)