SLITRK1 Antibody - BSA Free

Western Blot: SLITRK1 Antibody [NBP1-77319] - Western blot analysis of SLITRK1 in human brain tissue lysate with SLITRK1 antibody at (A) 1 and (B) 2 ug/mL.

Immunohistochemistry: SLITRK1 Antibody [NBP1-77319] - Immunofluorescence of Slitrk1 in mouse brain tissue with Slitrk1 Antibody at 20 ug/mL. Green: Slitrk1 antibody (NBP1-77319). Red: Phylloidin staining. Blue: DAPI staining.

Immunohistochemistry: SLITRK1 Antibody - BSA Free [NBP1-77319] - Immunofluorescence of slitrk1 in human brain tissue with slitrk1 antibody at 20 ug/mL.

Immunohistochemistry: SLITRK1 Antibody - BSA Free [NBP1-77319] - Immunohistochemistry of SLITRK1 in mouse brain tissue with SLITRK1 Antibody at 5 ug/mL.

Immunohistochemistry: SLITRK1 Antibody - BSA Free [NBP1-77319] - Immunohistochemistry of SLITRK1 in human brain tissue with SLITRK1 antibody at 2.5 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

SLITRK1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit SLITRK1 Antibody - BSA Free (NBP1-77319) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 18 amino acid synthetic peptide from near the center of human Slitrk1. The immunogen is located within amino acids 270 - 320 of Slitrk1. Amino Acid Squence: PTPFKTNGQEDHATPGSA
• Specificity: This antibody is predicted to have no cross-reactivity to other Slitrk proteins.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SLITRK1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 2.5 ug/mL
  • Immunohistochemistry-Paraffin
  • Western Blot 1-2 ug/mL
• Control Peptide:

  SLITRK1 Peptide (NBP1-77319PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for SLITRK1 Antibody - BSA Free

• FLJ54428
• KIAA1910KIAA0918
• leucine rich repeat containing 12
• Leucine-rich repeat-containing protein 12
• LRRC12
• RP11-395N17.1
• SLIT and NTRK-like family, member 1
• SLIT and NTRK-like protein 1
• slit and trk like gene 1
• SLITRK1
• TTM

Background

SLIT and NTRK-like family 1 (Slitrk1) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk1 is expressed primarily in mature neurons. Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth. While Slitrk1 variants have been suggested associated with Tourette's Syndrome, it is thought to play only a minor role if at all. This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLITRK1
• Uniprot:
  • NP_443142()