SLC22A17 Antibody

Immunohistochemistry-Paraffin: SLC22A17 Antibody [NBP1-20975] - (2ug/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Immunohistochemistry-Paraffin: SLC22A17 Antibody [NBP1-20975] - (2ug/ml) staining of paraffin embedded Human Cerebellum. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

• Reactivity: Hu
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

SLC22A17 Antibody Summary

• Immunogen: Peptide with sequence C-PETKRKLLPEVLRD corresponding to internal region according to NP_057693.3.
• Epitope: C terminus
• Specificity: This antibody is expected to recognize both reported isoforms NP_065105.2 and NP_057693.3).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SLC22A17
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 2 ug/ml
  • Peptide ELISA Detection limit 1:64000
  • Western Blot 0.1 ug/ml
• Application Notes: Western blot: Preliminary experiments gave an approx 150kDa band in Human Cerebellum lysates after 0.1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 57.7kDa according to NP_065105.2. The 150kDa band was successfully blocked by incubation with the immunizing peptide.
  IHC: Paraffin embedded Human Brain (Cortex and Cerebellum).

Reactivity Notes

Expected from sequence similarity: Mouse, Rat, Canine, and Bovine

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SLC22A17 Antibody

• 24p3R
• BOCTNGALR3
• BOIThBOIT
• Brain-type organic cation transporter
• Lipocalin-2 receptor
• Neutrophil gelatinase-associated lipocalin receptor
• NgalR
• NGALR2
• NGALRNGAL receptor
• potent brain type organic ion transporter
• solute carrier family 22 (organic cation transporter), member 17
• solute carrier family 22 member 17,24p3 receptor
• solute carrier family 22, member 17

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SLC22A17 Antibody (NBP1-20975)(2)

Publications using NBP1-20975

• Chuang HY, Jeng WY, Wang E et al. Secreted Neutrophil Gelatinase-Associated Lipocalin Shows Stronger Ability to Inhibit Cyst Enlargement of ADPKD Cells Compared with Nonsecreted Form Cells 2022-01-30 [PMID: 35159293]
• Devireddy LR, Gazin C, Zhu X, Green MR. A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptake. Cell 2005-12-29 [PMID: 16377569]

Bioinformatics

• Gene Symbol: SLC22A17
• Entrez:
  • 51310(Human)
  • 59049(Mouse)
  • 305886(Rat)
• Uniprot:
  • NP_065105.2(Human)