Siglec-3/CD33 Antibody (WM53) [Alexa Fluor® 488]


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Product Details

Reactivity HuSpecies Glossary
Applications Flow, ICC/IF
Alexa Fluor 488

Order Details

Siglec-3/CD33 Antibody (WM53) [Alexa Fluor® 488] Summary

Human AML cells
Cell surface
Recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immuno-receptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
IgG1 Kappa
Protein A or G purified
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  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence

Packaging, Storage & Formulations

Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Protein A or G purified


Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Siglec-3/CD33 Antibody (WM53) [Alexa Fluor® 488]

  • CD33 antigen (gp67)
  • CD33 antigen
  • CD33 molecule
  • CD33
  • FLJ00391
  • gp67
  • myeloid cell surface antigen CD33
  • p67
  • sialic acid binding Ig-like lectin 3
  • Sialic acid-binding Ig-like lectin 3
  • Siglec3
  • Siglec-3
  • SIGLEC3gp67


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-34511AF350
Alexa Fluor 405 NBP2-34511AF405
Alexa Fluor 488 NBP2-34511AF488
Alexa Fluor 532 NBP2-34511AF532
Alexa Fluor 594 NBP2-34511AF594
Alexa Fluor 647 NBP2-34511AF647
Alexa Fluor 700 NBP2-34511AF700
Alexa Fluor 750 NBP2-34511AF750
Allophycocyanin NBP2-34511APC
Allophycocyanin/Cy7 NBP2-34511APCCY7
Biotin NBP2-34511B
DyLight 350 NBP2-34511UV
DyLight 405 NBP2-34511V
DyLight 488 NBP2-34511G
DyLight 550 NBP2-34511R
DyLight 594 NBP2-34511DL594
DyLight 650 NBP2-34511C
DyLight 680 NBP2-34511FR
DyLight 755 NBP2-34511IR
FITC NBP2-34511F
Janelia Fluor 549 NBP2-34511JF549
Janelia Fluor 646 NBP2-34511JF646
PE NBP2-34511PE
PE/Atto594 NBP2-34511PEATT594
PE/Cy5.5 NBP2-34511PECY55
PE/Cy7 NBP2-34511PECY7
PerCP NBP2-34511PCP

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Gene Symbol CD33