Serpin A8/Angiotensinogen Antibody (369439) [Alexa Fluor® 488]

• Applications: WB
• Clone: 369439
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

Serpin A8/Angiotensinogen Antibody (369439) [Alexa Fluor® 488] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Serpin A8/Angiotensinogen
  Asp34-Ala485
  Accession # P01019
• Specificity: Detects human Serpin A8/Angiotensinogen in direct ELISAs and Western blots. Shows no cross-reactivity with recombinant human Serpin A1, -A3, -A4, -A5, -A6, -C1, -D1, -E2, -F1, -F2, -G1, -I1, -I2, -B6, -B8, -B9, or recombinant mouse Serpin A6.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Angiotensinogen, a member of the serpin family (Serpin A8), is synthesized in liver and cleaved by renin to produce angiotensin I. This is further processed by angiotensin converting enzyme (ACE) to yield angiotensin II, a key blood pressure regulator. The amino acid sequence of human AGT is 99%, 68%, 64%, and 61% identical to that of chimpanzee, canine, rat, and mouse.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.