Serine Palmitoyltransferase 2 Antibody

Images

 
Western Blot: Serine Palmitoyltransferase 2 Antibody [NBP2-20308] - Serine Palmitoyltransferase 2 levels in human neuroblastoma cells. Cells were untreated or treated with various drugs. Image from verified customer ...read more
Immunohistochemistry-Paraffin: Serine Palmitoyltransferase 2 Antibody [NBP2-20308] - Immunohistochemical analysis of paraffin-embedded Hepatoma, using antibody at 1:500 dilution.
Western Blot: Serine Palmitoyltransferase 2 Antibody [NBP2-20308] - Sample (30 ug of whole cell lysate) A: IMR32 7. 5% SDS PAGE gel, diluted at 1:1000.
Western Blot: Serine Palmitoyltransferase 2 Antibody [NBP2-20308] - Sample (50 ug of whole cell lysate) A: Mouse Liver, 7. 5% SDS PAGE gel, diluted at 1:500.

Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Serine Palmitoyltransferase 2 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human Serine palmitoyltransferase 2. The exact sequence is proprietary.
Localization
Endoplasmic reticulum membrane; Single-pass membrane protein
Predicted Species
Rat (95%), Bovine (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SPTLC2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
63 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Chicken (84%), Xenopus laevis (80%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Preservative
0.01% Thimerosal
Purity
Immunogen affinity purified

Alternate Names for Serine Palmitoyltransferase 2 Antibody

  • EC 2.3.1
  • EC 2.3.1.50
  • KIAA0526HSN1C
  • LCB 2
  • LCB2A
  • LCB2NSAN1C
  • Long chain base biosynthesis protein 2
  • Long chain base biosynthesis protein 2a
  • serine palmitoyltransferase 2
  • serine palmitoyltransferase, long chain base subunit 2
  • serine palmitoyltransferase, subunit II
  • Serine-palmitoyl-CoA transferase 2
  • SPT 2
  • SPT2

Background

This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SPTLC2
Uniprot