Senataxin Antibody

Images

 
Western Blot: Senataxin Antibody [NB100-57543] - Detection of Human Senataxin on HeLa whole cell lysate using NB100-57543. Senataxin was also immunoprecipitated by rabbit anti-Senataxin antibody NB100-57542.
Western Blot: Senataxin Antibody [NB100-57543] - Detection of Human Senataxin by Western Blot. Samples: Whole cell lysate (15 and 50 ug) from HeLa cells prepared using NETN lysis buffer. Antibody: Affinity purified ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ChIP, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml
 

Independent Antibodies

       

Senataxin Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 2627 and 2677 of human senataxin (NP_055861.2).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SETX
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000-1:5000
  • Chromatin Immunoprecipitation
  • Immunoprecipitation 2 - 10 ug/mg lysate
Application Notes
Use in chromatin immunoprecipitation reported in scientific literature (PMID 26700805)
Theoretical MW
302 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using
NB100-57543 in the following applications:

  • 1 publication
  • IP
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Senataxin Antibody

  • ALS4recessive, non-Friedreich type 1
  • AOA2FLJ43459
  • DKFZp781B151
  • KIAA0625FLJ12840
  • senataxin
  • SETX

Background

Mutations in Senataxin result in the neurodegenerative disorders Ataxia-Oculomotor Apraxia 2 (AOA2) and amyotrophic lateral sclerosis (ALS4). Senataxin bears an RNA/DNA helicase domain suggesting a role in DNA and RNA processing and has recently been found to be involved in the DNA damage response. Alternate names for Senataxin include SEN1 homolog, SETX, ALS4, KIAA0625, SCAR1, and AOA2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Senataxin Antibody (NB100-57543)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ChIP, IP.


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ChIP
(1)
IP
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol
ChIP Video Protocol
ChIP Webinar

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SETX
Entrez
Uniprot