Western Blot: Senataxin Antibody [NB100-57543] - Detection of Human Senataxin on HeLa whole cell lysate using NB100-57543. Senataxin was also immunoprecipitated by rabbit anti-Senataxin antibody NB100-57542.
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. Use in chromatin immunoprecipitation reported in scientific literature (PMID 26700805)
302 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publication using NB100-57543 in the following applications:
Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Rhesus Monkey, Chimpanzee and Crab-eating macaque.
Alternate Names for Senataxin Antibody
ALS4recessive, non-Friedreich type 1
Mutations in Senataxin result in the neurodegenerative disorders Ataxia-Oculomotor Apraxia 2 (AOA2) and amyotrophic lateral sclerosis (ALS4). Senataxin bears an RNA/DNA helicase domain suggesting a role in DNA and RNA processing and has recently been found to be involved in the DNA damage response. Alternate names for Senataxin include SEN1 homolog, SETX, ALS4, KIAA0625, SCAR1, and AOA2.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.