SEC61A Antibody


Western Blot: SEC61A Antibody [NBP1-31267] - Sample (30 ug of whole cell lysate) A: K562 10% SDS PAGE; antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: SEC61A Antibody [NBP1-31267] - Analysis of methanol-fixed A431, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: SEC61A Antibody [NBP1-31267] - Paraffin-embedded Cal27 xenograft, using antibody at 1:500 dilution.
Western Blot: SEC61A Antibody [NBP1-31267] - Analysis of SEC61A Antibody on: A: A431 10% SDS PAGE diluted at 1:1000

Product Details

Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
1.0 mg/ml

Order Details

SEC61A Antibody Summary

Synthetic peptide contain a sequence corresponding to a region within amino acids 413 and 426 (P61619) of SEC61A1
Endoplasmic reticulum membrane
Predicted Species
Mouse (100%), Rat (100%), Porcine (100%), Canine (100%), Zebrafish (100%), Xenopus (93%), Bovine (100%), Primate (100%)
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
1XPBS, 10% Glycerol (pH7).
0.01% Thimerosal
1.0 mg/ml
Immunogen affinity purified


Application Notes
Dot, Immunohistochemistry-Paraffin. The usefulness of this product in other applications has not been determined.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
52 kDa

Reactivity Notes

Expected cross reactivity based on sequence identity: Xenopus laevis (93%), Xenopus Tropicalis (100%), Rhesus Monkey (100%).

Alternate Names for SEC61A Antibody

  • HSEC61
  • protein transport protein SEC61 alpha subunit
  • protein transport protein Sec61 subunit alpha isoform 1
  • protein transport protein Sec61 subunit alpha
  • Sec61 alpha 1 subunit (S. cerevisiae)
  • Sec61 alpha-1
  • sec61 homolog
  • SEC61
  • SEC61A


SEC61A belongs to the SECY/SEC61 alpha family. It has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum.The SEC61 complex is responsible for translocation of proteins across the rough endoplasmic reticulum membrane. SEC61 is composed of three subunits: alpha, beta, and gamma; that associate to form a heterotrimer. Multiple heterotrimers associate forming the ER translocon. SEC61 alpha is a polytopic protein that has ten membrane-spanning loops. SEC61 has been found to be tightly associated with membrane bound ribosomes, either directly or through adapter proteins, and is required for assembly of membrane and secretory proteins.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

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Contact Information

Product PDFs


Gene Symbol SEC61A1

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