Species: Hu, Mu, Rt, Po, Bv, Ca, RM, Ze
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Applications: WB, ELISA, PA, AP
Applications: RNAi, RNAi SP
SEC61A belongs to the SECY/SEC61 alpha family. It has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum.The SEC61 complex is responsible for translocation of proteins across the rough endoplasmic reticulum membrane. SEC61 is composed of three subunits: alpha, beta, and gamma; that associate to form a heterotrimer. Multiple heterotrimers associate forming the ER translocon. SEC61 alpha is a polytopic protein that has ten membrane-spanning loops. SEC61 has been found to be tightly associated with membrane bound ribosomes, either directly or through adaptor proteins, and is required for assembly of membrane and secretory proteins.
|Product By Gene ID
- sec61 homolog
- protein transport protein Sec61 subunit alpha isoform 1
- Sec61 alpha-1
- protein transport protein Sec61 subunit alpha
- protein transport protein SEC61 alpha subunit
- Sec61 alpha 1 subunit (S. cerevisiae)
Bioinformatics Tool for SEC61A
Discover related pathways, diseases and genes to SEC61A. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.