Nav1.5 Antibody (4G8:1G7)

Images

 
Immunocytochemistry/ Immunofluorescence: Nav1.5 Antibody (4G8-1G7) [NB110-61010] - Figure A: Plasma membrane localisation of Nav1.5 identified by 4G8:1G7 detected by anti-mouse Alexa Fluor-488 conjugated antibody; ...read more
Flow Cytometry: Nav1.5 Antibody (4G8:1G7) [NB110-61010] - An intracellular stain was performed on U2OS cells with Nav1.5 Antibody [4G8:1G7] NB110-61010PE (blue) and a matched isotype control (orange). Cells were fixed ...read more
Flow Cytometry: Nav1.5 Antibody (4G8:1G7) [NB110-61010] - An intracellular stain was performed on MG-63 cells with Nav1.5 Antibody [4G8:1G7] NB110-61010PE (blue) and a matched isotype control (orange). Cells were fixed ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC, IP, RIA, CyTOF-ready
Clone
4G8:1G7
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Nav1.5 Antibody (4G8:1G7) Summary

Immunogen
Peptide (14mer) from an extracellular domain of Nav1.5 - VSENIKLGNLSALR
Isotype
IgM
Clonality
Monoclonal
Host
Mouse
Gene
SCN5A
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100 - 1:2000
  • ELISA 1:100 - 1:2000
  • Flow Cytometry 1:10 - 1:1000
  • Immunocytochemistry/Immunofluorescence 1:10 - 1:500
  • Immunohistochemistry 1:10 - 1:500
  • Immunoprecipitation 1:10 - 1:500
  • Radioimmunoassay 1:100 - 1:2000
  • CyTOF-ready
Application Notes
In the mouse brain, 3 main isoforms have been described of 180,140 and 120 kDa MW. A Western blot of 2 year old pediatric brain revealed bands of 180,140 and 120 kDa (weakly) with ERIC-1. This antibody is CyTOF ready.
Control
Nav1.5 Knockout HeLa Cell Lysate

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A or G purified

Notes

Positive control(s): Neuroblastome.

Alternate Names for Nav1.5 Antibody (4G8:1G7)

  • cardiac sodium channel alpha subunit
  • cardiac tetrodotoxin-insensitive voltage-dependent sodium channel alpha subunit
  • CDCD2VF1
  • HB1sodium channel, voltage-gated, type V, alpha (long QT syndrome 3)
  • HB2
  • HBBD
  • HH1CMD1E
  • ICCD
  • IVF
  • LQT3SSS1CMPD2
  • Nav1.5
  • PFHB1
  • Sodium channel protein cardiac muscle subunit alpha
  • sodium channel protein type 5 subunit alpha
  • sodium channel protein type V alpha subunit
  • Sodium channel protein type V subunit alpha
  • sodium channel, voltage-gated, type V, alpha subunit
  • Voltage-gated sodium channel subunit alpha Nav1.5

Background

Voltage-gated sodium channesl (VGSCs) mediate regenerative cell membrane depolarization and conduction of electrical signaling in nerves and muscles. Expression is also detected in lymphocytes, glia, and fibroblasts. VGSC proteins are comprised of a core alpha-subunit, together with one or more additional regulatory beta-subunit. Expression has been detected in a number of tumor cell lines and has been implicated in the metastatic behavior of breast and prostate cancer cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-12897
Species: Hu, Mu, Rt, Ha
Applications: WB, ICC/IF, IHC, IHC-P, IP, MiAr
NBP3-03109
Species: Hu, Mu, Rt
Applications: WB, IHC
H00003753-M01
Species: Hu, Rt, Ca, Gp, Pm
Applications: WB, ELISA, ICC/IF, RNAi, S-ELISA
NBP2-38146
Species: Hu
Applications: IHC, IHC-P
NBP2-12900
Species: Hu, Mu, Rt, Pm
Applications: WB, ICC/IF, IHC, IHC-P, MiAr
AF904
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, Neut
NBP2-58876
Species: Hu
Applications: ICC/IF
NBP1-47615
Species: Hu, Mu, Rt, Pm
Applications: WB, ICC/IF, IHC, IHC-P, MiAr
NBP1-46568
Species: Mu, Rt
Applications: WB, IHC, IHC-P
NBP2-84125
Species: Hu
Applications: WB, IHC, IHC-P
NBP2-12904
Species: Hu, Mu, Rt, Ha
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP

Publications for Nav1.5 Antibody (NB110-61010) (0)

There are no publications for Nav1.5 Antibody (NB110-61010).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Nav1.5 Antibody (NB110-61010) (0)

There are no reviews for Nav1.5 Antibody (NB110-61010). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Nav1.5 Antibody (NB110-61010). (Showing 1 - 1 of 1 FAQ).

  1. The customer has requested to see any western blot data that you have available for this antibody.
    • For our product NB110-61010, we have validated the western blot application by customer review. Unfortunately, the customer review did not come with an image. As this is a listed application on our webpage, we will fully guarantee western blot detection of human Nav1.5 with this product. Here is a link of our guarantee for your customer's reference. I am sorry that we did not have the data requested by your customer. Please let me know if they have any additional questions.

Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Additional Nav1.5 Products

Bioinformatics Tool for Nav1.5 Antibody (NB110-61010)

Discover related pathways, diseases and genes to Nav1.5 Antibody (NB110-61010). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Nav1.5 Antibody (NB110-61010)

Discover more about diseases related to Nav1.5 Antibody (NB110-61010).
 

Pathways for Nav1.5 Antibody (NB110-61010)

View related products by pathway.

PTMs for Nav1.5 Antibody (NB110-61010)

Learn more about PTMs related to Nav1.5 Antibody (NB110-61010).

Blogs on Nav1.5

There are no specific blogs for Nav1.5, but you can read our latest blog posts.
Coronavirus Brochure

Customers Who Bought This Also Bought

Contact Information

Learn the difference between western blot and simple western

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Nav1.5 Antibody (4G8:1G7) and receive a gift card or discount.

Bioinformatics

Gene Symbol SCN5A
Entrez