SCN4B Antibody - BSA Free

Western Blot: SCN4B Antibody [NBP2-93760] - Analysis of extracts of various cell lines, using SCN4B at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 90s.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

SCN4B Antibody - BSA Free Summary

• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-228 of mouse SCN4B (Q7M729). IDGIVKNDKSDPKVRVKDDDRITLEGSTKEKTNNISILLSDLEFSDTGRYTCFVRNPKEKDLNNSATIFLQVVDKLEKVDNTVTLIILAVVGGVIGLLVCILLLKKLITFILKKTREKKKECLVSSSGNDNTENGLPGSKAEEKPPTKV
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SCN4B
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:2000
• Theoretical MW: 25 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for SCN4B Antibody - BSA Free

• sodium channel beta-4 subunit
• sodium channel subunit beta-4
• sodium channel, voltage-gated, type IV, beta

Background

The protein encoded by the SCN4B gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SCN4B