SCN4B Products

Description

The protein encoded by the SCN4B gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.

Bioinformatics

Entrez	6330 Human
Uniprot	Q8IWT1 Human NP_777594 Human
Product By Gene ID	6330
Alternate Names	sodium channel subunit beta-4 sodium channel beta-4 subunit sodium channel, voltage-gated, type IV, beta

Diseases related to SCN4B

Discover more about diseases related to SCN4B.

Cardiac Arrhythmia
Long Qt Syndrome
Brugada Syndrome (disorder)
Channelopathies
Alzheimer's Disease
Cardiac Death
Pain Syndrome
Sudden Infant Death Syndrome
Erythromelalgia
Pain
Cardiac Arrest
Sudden Cardiac Death
Syncope
Atrial Fibrillation
Malignant Paraganglionic Neoplasm
Cardiac Fibrillation
Tachycardia, Ventricular

Pathways for SCN4B

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Pathogenesis
Cardiac Conduction
Cell Adhesion
Protein Glycosylation
Membrane Repolarization
Cell Development
Glycosylation
Synaptic Transmission
Hypersensitivity
Blood Circulation
Localization

PTMs for SCN4B

Learn more about PTMs related to SCN4B.

Cleavage

Bioinformatics Tool for SCN4B

Discover related pathways, diseases and genes to SCN4B. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.