SCGF/CLEC11a Antibody [Unconjugated]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Unconjugated
• Concentration: LYOPH

SCGF/CLEC11a Antibody [Unconjugated] Summary

• Immunogen: E. coli-derived recombinant human SCGF-beta
  Gly19-Phe245
  Accession # BAA21499
• Specificity: Detects human SCGF/CLEC11a in direct ELISAs and Western blots.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: CLEC11A
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SCGF/CLEC11a Antibody [Unconjugated]

• CLEC11a
• CLECSF3
• LSLCL
• P47
• SCGF

Background

SCGF is a secreted sulfated glycoprotein that belongs to the C-type lectin superfamily and is expressed primarily in hematopoietic tissues. It functions as a growth factor for primitive hematopoietic progenitor cells. SCGF-beta is a truncated variant of SCGF that has a 78 amino acid residue deletion and lacks a functional calcium‑dependent carbohydrate-recognition domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SCGF/CLEC11a Antibody (AF1904)(1)

Publication using AF1904

• Bo Shen, Kristy Vardy, Payton Hughes, Alpaslan Tasdogan, Zhiyu Zhao, Rui Yue et al. Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass eLife 2019-01-11 [PMID: 30632962]

Bioinformatics

• Gene Symbol: CLEC11A
• Uniprot:
  • BAA21499()