SCF/c-kit Ligand Antibody (371907)

• Reactivity: Ca, Fe
• Applications: WB
• Clone: 371907
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

SCF/c-kit Ligand Antibody (371907) Summary

• Immunogen: E. coli-derived recombinant canine SCF/c‑kit Ligand
  Lys26-Ala190
  Accession # Q06220
• Specificity: Detects canine and feline SCF/c-kit Ligand in direct ELISAs and Western blots. In direct ELISAs and Western blots, 50%-100% cross-reactivity with recombinant human (rh) SCF and recombinant mouse SCF is observed and no cross-reactivity with rhM-CSF is observed.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: KITLG
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SCF/c-kit Ligand Antibody (371907)

• c-kit Ligand
• DCUA
• DFNA69
• DKFZp686F2250
• familial progressive hyperpigmentation 2
• FPH2
• FPHH
• KIT ligand
• Kitl
• KITLG
• KL-1
• Mast cell growth factor
• MGF
• MGFSHEP7
• SCF
• SCFStem cell factor
• SFc-Kit ligand
• SHEP7
• SLF
• steel factor

Background

SCF, also known as c-kit ligand, is a 28 kDa-40 kDa type I transmembrane (TM) glycoprotein that plays important roles in fetal and adult developmental processes. Endothelial cells, fibroblasts, and keratinocytes can express SCF. The 190 aa extracellular region contains a proteolytic cleavage site, generating 165 aa circulating monomers and noncovalent homodimers. Soluble feline and canine SCF share 93% aa identity with each other and 88%-92% aa identity with pig, cow, sheep, goat, horse, and mink SCF.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KITLG
• Uniprot:
  • Q06220()