S1P3/EDG-3 Antibody - BSA Free

Immunohistochemistry-Paraffin: S1P3/EDG-3 Antibody [NBP3-14467] - Immunohistochemistry of formalin-fixed, paraffin-embedded human ovary carcinoma after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: S1P3/EDG-3 Antibody [NBP3-14467] - Immunohistochemistry of formalin-fixed, paraffin-embedded human prostate carcinoma after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: S1P3/EDG-3 Antibody [NBP3-14467] - Immunohistochemistry of formalin-fixed, paraffin-embedded human kidney after heat-induced antigen retrieval.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

S1P3/EDG-3 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 16 amino acid peptide from N-Terminus extracellular domain of human S1P3/EDG-3.
• Epitope: N-Terminus
• Specificity: Human S1P3/EDG-3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: S1PR3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: .

Reactivity Notes

Expected reactivity based on percent sequence identity: Gorilla, Marmoset (87%), Rabbit (80%)

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for S1P3/EDG-3 Antibody - BSA Free

• EDG3
• EDG-3
• EDG3FLJ37523
• Endothelial differentiation G-protein coupled receptor 3
• endothelial differentiation, sphingolipid G-protein-coupled receptor, 3
• FLJ93220
• G protein-coupled receptor, endothelial differentiation gene-3
• LPB3
• MGC71696
• S1P receptor 3
• S1P receptor EDG3
• S1P receptor Edg-3
• S1P3
• S1PR3
• sphingosine 1-phosphate receptor 3
• Sphingosine 1-phosphate receptor Edg-3
• sphingosine-1-phosphate receptor 3

Background

EDG3, a Lysophospholipid/Lysosphingolipid Receptor, binds the vasoconstrictor sphingosine-1-phosphate and activates transcription of serum response element-driven reporter genes. EDG3 may regulate angiogenesis and vascular endothelial cell functions. EDG3 has been reported in all tissues, with highest levels in heart, placenta, kidney, and liver. ESTs have been isolated from placenta and germ cell tumor libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: S1PR3