S1P1/EDG-1 Antibody (713412) [Unconjugated]


Mouse thymocytes were stained with Rat Anti-Mouse CD4 PE‑conjugated Monoclonal Antibody (Catalog # FAB554P) and either (A) Rat Anti-Mouse S1P1/EDG‑1 Monoclonal Antibody (Catalog # MAB7089) or (B) Rat IgG2A Isotype ...read more
HEK293 human embryonic kidney cell line transfected with mouse S1P1/EDG‑1 and GFP was stained with (A) Rat Anti-Mouse S1P1/EDG‑1 Monoclonal Antibody (Catalog # MAB7089) or (B) Rat IgG2A isotype control antibody ...read more
S1P1/EDG‑1 was detected in perfusion fixed frozen sections of mouse heart using Rat Anti-Mouse S1P1/EDG‑1 Monoclonal Antibody (Catalog # MAB7089) at 25 µg/mL overnight at 4 °C. Tissue was stained using the ...read more

Product Details

Reactivity MuSpecies Glossary
Applications Flow, IHC, CyTOF-ready

S1P1/EDG-1 Antibody (713412) [Unconjugated] Summary

Mouse S1P1/EDG‑1 synthetic peptide (T4-H28)
Accession # O08530
Detects mouse S1P1/EDG‑1 peptide in direct ELISAs.
Details of Functionality
ActivityAssaywCitation not found None None
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Flow Cytometry 0.25 ug/10^6 cells
  • Immunohistochemistry 8-25 ug/mL
  • CyTOF-ready
Read Publications using
MAB7089 in the following applications:

Packaging, Storage & Formulations

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
No Preservative
Reconstitution Instructions
Sterile PBS to a final concentration of 0.5 mg/mL.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for S1P1/EDG-1 Antibody (713412) [Unconjugated]

  • CD363 antigen
  • CD363
  • CHEDG1
  • D1S3362
  • EDG1
  • EDG-1
  • EDG1edg-1
  • Endothelial differentiation G-protein coupled receptor 1
  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 1
  • FLJ58121
  • S1P receptor 1
  • S1P receptor Edg-1
  • S1P1
  • S1P1ECGF1
  • S1PR1
  • sphingosine 1-phosphate receptor 1
  • sphingosine 1-phosphate receptor EDG1
  • Sphingosine 1-phosphate receptor Edg-1
  • sphingosine-1-phosphate receptor 1


S1P1 (sphingosine 1-phosphate receptor-1), also known as EDG-1 (endothelial differentiation, G-protein coupled receptor-1) or S1PR1 (sphingosine-1-phosphate receptor 1) is a widely expressed, 37-40 kDa, G protein coupled receptor within the S1P subfamily of the EDG family. S1P1 is one of five receptors for the bioactive lipid S1P and mediates most of S1P effects on angiogenesis, vascular maturation, and cell migration, especially T cell egress from lymphoid organs. Human and mouse S1P1 share 84% amino acid identity within the N-terminal extracellular portion used as an immunogen.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for S1P1/EDG-1 Antibody (MAB7089)(16)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: Flow Cytometry.

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Showing Publications 1 - 10 of 16. Show All 16 Publications.
Publications using MAB7089 Applications Species
MJ McCarron, M Irla, A Sergé, SM Soudja, JC Marie Transforming Growth Factor-beta signaling in alphabeta thymocytes promotes negative selection Nat Commun, 2019;10(1):5690. 2019 [PMID: 31857584] (Flow Cytometry, Mouse) Flow Cytometry Mouse
K Shimano, Y Maeda, H Kataoka, M Murase, S Mochizuki, H Utsumi, K Oshita, K Sugahara Amiselimod (MT-1303), a novel sphingosine 1-phosphate receptor-1 functional antagonist, inhibits progress of chronic colitis induced by transfer of CD4+CD45RBhigh�T cells PLoS ONE, 2019;14(12):e0226154. 2019 [PMID: 31805144] (Flow Cytometry, Mouse) Flow Cytometry Mouse
J Choi, PT Rudak, S Lesage, SMM Haeryfar Glycolipid Stimulation of Invariant NKT Cells Expands a Unique Tissue-Resident Population of Precursors to Mature NK Cells Endowed with Oncolytic and Antimetastatic Properties J. Immunol., 2019;0(0):. 2019 [PMID: 31462506] (Flow Cytometry, Mouse) Flow Cytometry Mouse
MM Moretto, S Hwang, K Chen, IA Khan Complex and Multilayered Role of IL-21 Signaling during Thymic Development J. Immunol., 2019;0(0):. 2019 [PMID: 31341076] (Flow Cytometry, Mouse) Flow Cytometry Mouse
MJ Lang, M Mori, J Ruer-Laven, J Pieters A Coronin 1-Dependent Decision Switch in Juvenile Mice Determines the Population of the Peripheral Naive T Cell Compartment J. Immunol., 2017;0(0):. 2017 [PMID: 28821585] (Flow Cytometry, Mouse) Flow Cytometry Mouse
A Audemard-V, M Rivière, A Durand, E Peranzoni, V Guichard, P Hamon, N Bonilla, T Guilbert, A Boissonnas, C Auffray, G Eberl, B Lucas, B Martin Macrophages Induce Long-Term Trapping of ?? T Cells with Innate-like Properties within Secondary Lymphoid Organs in the Steady State J. Immunol., 2017;0(0):. 2017 [PMID: 28779024] (Flow Cytometry, Mouse) Flow Cytometry Mouse
DP Golec, RE Hoeppli, LM Henao Cavi, J McCann, MK Levings, TA Baldwin Thymic progenitors of TCR??(+) CD8?? intestinal intraepithelial lymphocytes require RasGRP1 for development J. Exp. Med., 2017;0(0):. 2017 [PMID: 28652304] (Flow Cytometry, Mouse) Flow Cytometry Mouse
A Mendoza, V Fang, C Chen, M Serasinghe, A Verma, J Muller, VS Chaluvadi, ML Dustin, T Hla, O Elemento, JE Chipuk, SR Schwab Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells Nature, 2017;0(0):. 2017 [PMID: 28538737] (Flow Cytometry, Mouse) Flow Cytometry Mouse
R Ruscher, RL Kummer, YJ Lee, SC Jameson, KA Hogquist CD8?? intraepithelial lymphocytes arise from two main thymic precursors Nat. Immunol., 2017;0(0):. 2017 [PMID: 28530714] (Flow Cytometry, Mouse) Flow Cytometry Mouse
VM Turner, NA Mabbott Ageing adversely affects the migration and function of marginal zone B cells Immunology, 2017;151(3):349-362. 2017 [PMID: 28369800] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Show All 16 Publications.

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB7089U
Alexa Fluor 405 FAB7089V
Alexa Fluor 488 FAB7089G
Alexa Fluor 594 FAB7089T
Alexa Fluor 647 FAB7089R
Alexa Fluor 700 FAB7089N
Alexa Fluor 750 FAB7089S
Allophycocyanin FAB7089A
Biotin FAB7089B
Phycoerythrin FAB7089P

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Gene Symbol S1PR1