S1P3/EDG-3 Antibody (SR1706) - BSA Free

Western Blot: S1P3/EDG-3 Antibody (SR1706) [NBP3-22313] - Western blot analysis using NBP3-22313 in HepG2 cell lysate.

• Reactivity: Hu
• Applications: WB, ICC/IF, IHC
• Clone: SR1706
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

S1P3/EDG-3 Antibody (SR1706) - BSA Free Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human S1P3/EDG-3 (Uniprot #: Q99500)
• Specificity: Detects endogenous levels of total S1P3/EDG-3
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: S1PR3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:50-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 42 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for S1P3/EDG-3 Antibody (SR1706) - BSA Free

• EDG3
• EDG-3
• EDG3FLJ37523
• Endothelial differentiation G-protein coupled receptor 3
• endothelial differentiation, sphingolipid G-protein-coupled receptor, 3
• FLJ93220
• G protein-coupled receptor, endothelial differentiation gene-3
• LPB3
• MGC71696
• S1P receptor 3
• S1P receptor EDG3
• S1P receptor Edg-3
• S1P3
• S1PR3
• sphingosine 1-phosphate receptor 3
• Sphingosine 1-phosphate receptor Edg-3
• sphingosine-1-phosphate receptor 3

Background

EDG3, a Lysophospholipid/Lysosphingolipid Receptor, binds the vasoconstrictor sphingosine-1-phosphate and activates transcription of serum response element-driven reporter genes. EDG3 may regulate angiogenesis and vascular endothelial cell functions. EDG3 has been reported in all tissues, with highest levels in heart, placenta, kidney, and liver. ESTs have been isolated from placenta and germ cell tumor libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: S1PR3