Ryk Antibody (SR2178) - BSA Free

Western Blot: Ryk Antibody (SR2178) [NBP3-22253] - Western blot analysis using NBP3-22253 in MCF7 cell lysate.

• Reactivity: Hu
• Applications: WB, Flow, ICC/IF, IHC, IP
• Clone: SR2178
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Ryk Antibody (SR2178) - BSA Free Summary

• Description: Novus Biologicals Rabbit Ryk Antibody (SR2178) - BSA Free (NBP3-22253) is a recombinant monoclonal antibody validated for use in IHC, WB, Flow, ICC/IF and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human Ryk (Uniprot #: P34925)
• Specificity: Detects endogenous levels of total Ryk
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: RYK
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:50
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:50-1:200
  • Immunoprecipitation 1:50
  • Western Blot 1:1000-1:5000
• Theoretical MW: 72 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Ryk Antibody (SR2178) - BSA Free

• D3S3195
• EC 2.7.10
• EC 2.7.10.1
• hydroxyaryl-protein kinase
• JTK5
• JTK5A protein tyrosine kinase
• JTK5A
• RYK receptor-like tyrosine kinase
• Ryk
• RYK1
• tyrosine-protein kinase RYK

Background

RYK (Receptor like Tyrosine kinase 1) is in the Tyrosine family of receptor kinases. It is found in the plasma membrane of heart, prostate and kidney cells. RYK contains 604 amino acids and it contains one WIF domain. It functions as a potential growth factor receptor protein tyrosine kinase. RYK are divergent from those of other classic receptor tyrosine kinases. It is an orphan receptor that contains a catalytically inactive tyrosine kinase related domain. RYK is expressed in nestin positive progenitor cells and neurons, and in a certain population of oligodendrocytes, O2A progenitor cells, and type 2 astrocytes in developing CNS.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RYK