RXR beta/NR2B2 Peptide

• Reactivity: Hu
• Applications: AC

RXR beta/NR2B2 Peptide Summary

• Description: A peptide to RXRB.
• Protein/Peptide Type: Peptide
• Gene: RXRB

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NB100-1467.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Preservative: No Preservative

Alternate Names for RXR beta/NR2B2 Peptide

• DAUDI6
• H-2RIIBP
• MHC class I promoter binding protein
• NR2B2
• NR2B2MGC1831
• Nuclear receptor subfamily 2 group B member 2
• RCoR-1
• retinoic acid receptor RXR-beta
• Retinoid X receptor beta
• retinoid X receptor, beta
• RXR beta
• RXRB

Background

Retinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma, all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta controls a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: RXRB