RUNX1/CBFA2 Antibody Blocking Peptide

Product Discontinued

RUNX1/CBFA2 Antibody Blocking Peptide Summary

• Description: A RUNX1/CBFA2 antibody blocking peptide.
• Immunogen: Blocking Peptide for NBP2-11256
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: RUNX1

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP2-11256.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Alternate Names for RUNX1/CBFA2 Antibody Blocking Peptide

• Acute myeloid leukemia 1 protein
• AML1
• AML1acute myeloid leukemia 1
• AML1-EVI-1
• CBFA2
• CBFA2acute myeloid leukemia 1 protein (oncogene AML-1), core-binding factor, alphasubunit10AMLCR1
• Core-binding factor subunit alpha-2
• EVI-1
• PEBP2A2
• runt domain, alpha subunit 2
• runt-related transcription factor 1
• RUNX1
• SL3/AKV core-binding factor alpha B subunit

Background

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: RUNX1