RUNX1/CBFA2 Antibody (751926) [Alexa Fluor® 488]

• Applications: WB, ICC/IF
• Clone: 751926
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

RUNX1/CBFA2 Antibody (751926) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human RUNX1/CBFA2
  Gly217-Tyr480
  Accession # Q01196-8
• Specificity: Detects human RUNX1/CBFA2 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) RUNX2 or rhRUNX3 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

RUNX1 (runt-related transcription factor 1), also known as CBFA2 (core-binding factor alpha 2) or AML1 (acute myelogenous leukemia 1), is a heterodimeric transcription factor that plays a role in normal hematopoiesis. Multiple splice variants exist. Defects in RUNX1 are associated with several types of leukemia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.