RND3 Antibody (687202) [Alexa Fluor® 405]

• Reactivity: Hu, Mu
• Applications: WB
• Clone: 687202
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

RND3 Antibody (687202) [Alexa Fluor® 405] Summary

• Immunogen: RND3 (RD1 peptide)
  Cys197-Arg207
  Accession # P61587
• Specificity: Detects human RND3 in direct ELISAs and Western blots.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for RND3 Antibody (687202) [Alexa Fluor® 405]

• ARHE
• MemB
• Protein MemB
• Rho family GTPase 3member E
• Rho8
• RHOE
• Rho-related GTP-binding protein Rho8
• rho-related GTP-binding protein RhoE
• RND3
• small GTP binding protein Rho8

Background

RND3, also known as RhoE, is an approximately 27 kDa member of the Rho family, small GTPase superfamily of molecules.  It is 244 amino acids (aa) in length, and the mature chain extends from aa 1-241.  RND3 is ubiquitously expressed and is involved in keratinocyte differentiation and stratification.  RND3 overexpression results in cell size enlargement and an increase in the number of stratified cells.  RND3 depletion results in hyperproliferation and delays initiation of keratinocyte differentiation.  Human RND3 shares 100% aa sequence identity with mouse RND3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • P61587()