RND3 Antibody (687202) [PerCP]

• Reactivity: Hu, Mu
• Applications: WB
• Clone: 687202
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: PerCP

RND3 Antibody (687202) [PerCP] Summary

• Immunogen: RND3 (RD1 peptide)
  Cys197-Arg207
  Accession # P61587
• Specificity: Detects human RND3 in direct ELISAs and Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: RND3
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for RND3 Antibody (687202) [PerCP]

• ARHE
• MemB
• Protein MemB
• Rho family GTPase 3member E
• Rho8
• RHOE
• Rho-related GTP-binding protein Rho8
• rho-related GTP-binding protein RhoE
• RND3
• small GTP binding protein Rho8

Background

RND3 is a gene that codes for a protein that binds GTP but is resistant to Rho-specific GTPase-activating proteins as well as lacks certain GTPase activities, and is 244 amino acids long and weighs approximately 27 kDa. Current studies are being done on several diseases and disorders relating to this gene including colon, gastric, lung and prostate cancers, glioblastoma, hypoxia, prostatitis, melanoma, and carcinoma. RND3 has also been shown to have interactions with SFN, ARHGAP5, PLXNB1, ROCK1, and UBXN11 in pathways such as the cytoskeletal signaling and selected targets of CREB1 and p53 pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RND3