RND3 Products

Description

RND3 is a gene that codes for a protein that binds GTP but is resistant to Rho-specific GTPase-activating proteins as well as lacks certain GTPase activities, and is 244 amino acids long and weighs approximately 27 kDa. Current studies are being done on several diseases and disorders relating to this gene including colon, gastric, lung and prostate cancers, glioblastoma, hypoxia, prostatitis, melanoma, and carcinoma. RND3 has also been shown to have interactions with SFN, ARHGAP5, PLXNB1, ROCK1, and UBXN11 in pathways such as the cytoskeletal signaling and selected targets of CREB1 and p53 pathways.

Bioinformatics

Entrez	390 Human
Uniprot	NM_005168 Human NP_005159 Human NP_005159.1 Human AAH12513 Human
Product By Gene ID	390
Alternate Names	Rnd3 RHOE ARHE RHO8 Rho-related GTP-binding protein Rho8 small GTP binding protein Rho8 Protein MemB rho-related GTP-binding protein RhoE Rho family GTPase 3member E

Diseases related to RND3

Discover more about diseases related to RND3.

Neoplasms
Malignant Neoplasms
Tissue Adhesions
Cell Invasion
Cell Transformation, Neoplastic
Carcinoma
Melanoma
Neoplasm Metastasis
Neoplasm Invasiveness
Carcinogenesis
Liver Carcinoma
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Lung
Malignant Neoplasm Of Stomach
Stomach Neoplasms
Non-small Cell Lung Carcinoma
Neurodegenerative Disorders
Nervousness
Lung Neoplasms
Growth Retardation

Pathways for RND3

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Cell Cycle
Localization
Cell Proliferation
Cell Migration
Cell Death
Cell Motility
Cell Growth
Cell Adhesion
Oncogenesis
Sensitization
Translation
Cell Cycle Arrest
Stress Fiber Assembly
Neuron Migration
Colony Morphology
Membrane Organization
Reflex
Axon Guidance
Cell Differentiation
Segmentation

Research Areas for RND3

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Signal Transduction

PTMs for RND3

Learn more about PTMs related to RND3.

Phosphorylation
Farnesylation
Ribosylation
Cleavage
Deacetylation
Methylation
Dephosphorylation
Geranylgeranylation
Prenylation
Ubiquitination

Bioinformatics Tool for RND3

Discover related pathways, diseases and genes to RND3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.