RIZ1 Antibody - Azide and BSA Free

Western Blot: RIZ1 Antibody [NBP2-94500] - Analysis of extracts of various cell lines, using RIZ1 at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 90s.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

RIZ1 Antibody - Azide and BSA Free Summary

• Description: Novus Biologicals Rabbit RIZ1 Antibody - Azide and BSA Free (NBP2-94500) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-176 of human RIZ1 (NP_036363.2). MNQNTTEPVAATETLAEVPEHVLRGLPEEVRLFPSAVDKTRIGVWATKPILKGKKFGPFVGDKKKRSQVKNNVYMWEVYYPNLGWMCIDATDPEKGNWLRYVNWACSGEEQNLFPLEINRAIYYKTLKPIAPGEELLVWYNGEDNPEIAAAIEEERASARSKRSSPKSRKGKKKSQ
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PRDM2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 50% glycerol
• Preservative: 0.05% Proclin 300
• Purity: Affinity purified

Alternate Names for RIZ1 Antibody - Azide and BSA Free

• EC 2.1.1.43
• GATA-3 binding protein G3B
• GATA-3-binding protein G3B
• KMT8PR domain-containing protein 2
• Lysine N-methyltransferase 8
• MTB-ZFHUMHOXY1
• PR domain containing 2, with ZNF domain
• PR domain zinc finger protein 2
• retinoblastoma protein-binding zinc finger protein
• Retinoblastoma protein-interacting zinc finger protein
• RIZ1
• RIZ2
• RIZMTE-binding protein
• Zinc finger protein RIZ
• zinc-finger DNA-binding protein

Background

RIZ1 (Retinoblastoma proteininteracting zinc finger), also known as PRDM2, is a nuclear protein containing 8 zinc finger motifs. RIZ1 contains a PR domain that may function as protein binding interface in the regulation of chromatin-mediated gene expression. RIZ 1 acts as a tumor suppressor, and RIZ 1 inactivation is common in many types of human cancers, including neuroendocrine, breast, liver, colon, skin, and lymphoid tumors. Similarly, RIZ1 over-expression in breast cancer cells caused cell cycle arrest in G2-M and apoptosis. RIZ1 is highly expressed in human retinoblastoma cells and at low levels in all other human cell lines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Bioinformatics

• Gene Symbol: PRDM2