RIG-I Antibody (SR1042) - BSA Free

Western Blot: RIG-I Antibody (SR1042) [NBP3-21782] - Western blot analysis using NBP3-21782 in Jurkat cell lysate.

• Reactivity: Hu
• Applications: WB, IP
• Clone: SR1042
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

RIG-I Antibody (SR1042) - BSA Free Summary

• Description: Novus Biologicals Rabbit RIG-I Antibody (SR1042) - BSA Free (NBP3-21782) is a recombinant monoclonal antibody validated for use in WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human RIG-I (Uniprot #: O95786)
• Specificity: Detects endogenous levels of total RIG-I
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: RIGI
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1:50
  • Western Blot 1:500-1:1000
• Theoretical MW: 107 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for RIG-I Antibody (SR1042) - BSA Free

• DDX58
• DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
• DEAD box protein 58
• DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide
• DKFZp686N19181
• EC 3.6.4.13
• FLJ13599
• probable ATP-dependent RNA helicase DDX58
• retinoic acid inducible gene I
• Retinoic acid-inducible gene 1 protein
• Retinoic acid-inducible gene I protein
• RIG-1
• RIGI
• RIG-I
• RIG-IDKFZp434J1111
• RNA helicase RIG-I

Background

RIG-I, also known as DDX58, consists of a 106.6 kDa and a 101.4 kDa isoform and is involved in recognizing viruses and activating a response. Current research is being conducted with diseases and disorders such as hepatitis, rubella, influenza, rabies, hemorrhagic fever, lupus nephritis, and tick-borne encephalitis. The protein interacts in pathways such as NF-kappa signaling, cytosolic DNA-sensing, measles, influenza A, and mediated induction pathways with proteins such as CYLD, ZC3HAV1, DDX3X, MAVS, and WRNIP1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RIGI