Ribosome maturation protein SBDS Antibody (1E8) - BSA Free

Western Blot: Shwachman Bodian-Diamond syndrome Antibody (1E8) [NBP2-22594] - Lane 1. 293T cell lysate, Lane 2. HeLa cell lysate.

Immunocytochemistry/Immunofluorescence: Shwachman Bodian-Diamond syndrome Antibody (1E8) [NBP2-22594] - Analysis in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human SBDS antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF
• Clone: 1E8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Ribosome maturation protein SBDS Antibody (1E8) - BSA Free Summary

• Description: Novus Biologicals Mouse Ribosome maturation protein SBDS Antibody (1E8) - BSA Free (NBP2-22594) is a monoclonal antibody validated for use in WB, ELISA and ICC/IF. Anti-Ribosome maturation protein SBDS Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant human Ribosome maturation protein SBDS (1-250aa) purified from E. coli
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: SBDS
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Western Blot 1:3000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 10% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for Ribosome maturation protein SBDS Antibody (1E8) - BSA Free

• FLJ10917
• ribosome maturation protein SBDS
• SDSCGI-97
• Shwachman-Bodian-Diamond syndrome protein
• Shwachman-Bodian-Diamond syndrome
• SWDS

Background

The Shwachman-Bodian-Diamond syndrome (SBDS) is 249 amino acid ribosome maturation protein. The precise function of the SBDS protein is not known but it appears to play an important role in actin cytoskeletal function and mitotic spindle stabilization. Also, SBDS is required for the assembly of mature ribosomes and ribosome biogenesis. Mutations in the SBDS gene cause Shwachman-Diamond syndrome (SDS). SDS is an autosomal recessive disorder with clinical features that include pancreatic exocrine insufficiency, haematological dysfunction and skeletal abnormalities.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Ribosome maturation protein SBDS Antibody (NBP2-22594)(1)

Publication using NBP2-22594

• Ohlson MB, Eitson JL, Wells AI et al. Genome-Scale CRISPR Screening Reveals Host Factors Required for Ribosome Formation and Viral Replication mBio 2023-04-25 [PMID: 36809113] (Western Blot)

Bioinformatics

• Gene Symbol: SBDS
• Uniprot:
  • NP_057122(Human)