REXO2 Antibody - Azide and BSA Free

Western Blot: REXO2 Antibody [NBP2-93904] - Analysis of extracts of various cell lines, using REXO2 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 3s.

Immunocytochemistry/Immunofluorescence: REXO2 Antibody [NBP2-93904] - Analysis of U-2 OS cells using REXO2 . Blue: DAPI for nuclear staining.

Immunocytochemistry/Immunofluorescence: REXO2 Antibody [NBP2-93904] - Analysis of L929 cells using REXO2 . Blue: DAPI for nuclear staining.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

REXO2 Antibody - Azide and BSA Free Summary

• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-237 of human REXO2 (NP_056338.2). VREGGAAMAAGESMAQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLNILAEGPNLIIKQPDELLDSMSDWCKEHHGKSGLTKAVKESTITLQQAEYEFLSFVRQQTPPGLCPLAGNSVHEDKKFLDKYMPQFMKHLHYRIIDVSTVKELCRRWYPEEYEFAPKKAASHRALDDISESIKELQFYRNNIFKKKIDEKKRKIIENGENEKTVS
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: REXO2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:50-1:100
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 50% glycerol
• Preservative: 0.01% Thimerosal
• Purity: Affinity purified

Alternate Names for REXO2 Antibody - Azide and BSA Free

• CGI-114
• DKFZp566E144
• EC 3.1
• oligoribonuclease, mitochondrial
• REX2
• REX2, RNA exonuclease 2 homolog (S. cerevisiae)
• RFN
• RNA exonuclease 2 homolog
• SFNMGC111570
• Small fragment nuclease
• SMFN

Background

REXO2, also known as Oligoribonuclease, mitochondrial, is a 27kDa 237 amino acid protein with a shorter 23kDa 199 isoform. This gene plays a significant role in reparing DNA and is believed to play a role in aiding cells resist UV-C-induced death. REXO2 has been studied in relation to t-cell leukemia, leukemia, tuberculosis and mycobacterium tuberculosis. REXO2 is linked to the ribosome biogenesis in eukaryotes pathway where it interacts with ATG5, MPG, DIS3, UBC and EXOSC10.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Bioinformatics

• Gene Symbol: REXO2