Reg3A Antibody

Immunohistochemistry-Paraffin: Reg3a Antibody [NBP2-27297] - Formalin-fixed, paraffin-embedded human intestine stained with REG3A antibody (5 ug/ml), peroxidase-conjugate and DAB chromogen.

Product Discontinued

Reg3A Antibody Summary

• Immunogen: A portion of amino acids 100-150 of human REG3A was used as the immunogen for this antibody.
• Predicted Species: Chimpanzee (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: REG3A
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5-7ug/ml
• Application Notes: Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.

Reactivity Notes

The amino acid sequence used as immunogen is 88% homologous in Mouse.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 ml PBS and 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein G purified

Alternate Names for Reg3A Antibody

• hepatocarcinoma-intestine-pancreas
• HIPpancreatitis-associated protein
• Human proislet peptide
• Lithostathine 3
• pancreatic beta cell growth factor
• Pancreatitis-associated protein 1
• PAP homologous protein
• PAP1FLJ18565
• PAP2
• PAPPAP-H
• PBCGF
• proliferation-inducing protein 34
• proliferation-inducing protein 42
• Reg III-alpha
• REG3
• Reg3A
• REG-3-alpha
• regenerating islet-derived 3 alpha
• regenerating islet-derived protein 3-alpha
• Regenerating islet-derived protein III-alpha
• REG-III

Background

REG3A, also known as Regenerating islet-derived protein 3 alpha, Reg III-alpha, and pancreatitis associated protein (PAP), is a 174 amino acid containing stress protein involved in the control of bacterial proliferation. REG3A is generally found in the apical region of pancreatic acinar cells and appears in pancreatic juice after induction of pancreatic inflammation. It has a possible role in inducing new pancreatic islets development. REG3A belongs to the Reg-related family with a C-type lectin domain and is constitutively expressed in intestine while low expression is found in healthy pancreas. Overexpression of REG3A is seen during the acute phase of pancreatitis and in some patients with chronic pancreatitis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: REG3A