Recombinant Rat LILRC2 Protein, CF


When Recombinant Rat LILRC2 (Catalog # 9808‑T4) is immobilized at 2 μg/mL, 100 μL/well, Recombinant Human Angiopoietin-like 7/ANGPTL7 (Catalog # 914‑AN) binds with an ED50 of 0.04‑0.24 μg/mL.

Product Details

Reactivity RtSpecies Glossary
Applications Bioactivity

Order Details

Recombinant Rat LILRC2 Protein, CF Summary

Details of Functionality
Measured by its binding ability in a functional ELISA. When Recombinant Rat LILRC2 is immobilized at 2 μg/mL,100 μL/well, the concentration of Recombinant Human Angiopoietin-like 7/ANGPTL7 (Catalog # 914-AN) that produces 50% of the optimal binding response is 0.04-0.24 μg/mL
Mouse myeloma cell line, NS0-derived rat LILRC2 protein
Met1-Asn230, with a C-terminal 6-His tag
Accession #
N-terminal Sequence
Protein/Peptide Type
Recombinant Proteins
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Note
<0.10 EU per 1 μg of the protein by the LAL method.


  • Bioactivity
Theoretical MW
24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
32-43 kDa, reducing conditions

Packaging, Storage & Formulations

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS.
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Reconstitution Instructions
Reconstitute at 500 μg/mL in PBS.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Recombinant Rat LILRC2 Protein, CF

  • LILRC2


The leukocyte immunoglobulin-like receptors (LILR) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIRs) (1). LILRC2 (leukocyte immunoglobulin-like receptor C2) is a 35 kDa member of the LILRs that are expressed on hematopoietic cells. Mature rat LILRC2 is a type I transmembrane (TM) protein that is 241 amino acids (aa) in length. It contains a 207 aa extracellular domain (ECD), a 19 aa TM segment, and a short cytoplasmic tail (2). The ECD contains two Ig-like domains while the TM segment possesses an Arg residue (2, 3). This suggests that LILRC2 is an activating receptor that may interact with Fc epsilon RI gamma and/or CD3 zeta. Cells expressing LILRC2 include neutrophils, B cells, and CD4+ and CD8+ T cells (2). No human or mouse LILRC2 is known. Rat LILRC2 shares 47.9% identity with LILRC1. R&D Systems in-house testing indicates that LILRC2 binds to Angiopoietin-like 7, consistent with the demonstrated functional interactions between other members of these protein families (4).
  1. Thomas, R. et al. (2010) Clin. Rev. Allergy Immunol. 38:159.
  2. Hoelsbrekken, S.E. et al. (2005) Immunogenetics 57:479.
  3. Shiroishi, M. et al. (2006) J. Biol. Chem. 281:19536.
  4. Zhang, C.C. et al. (2012) Nature 485:656.

Customers Who Viewed This Item Also Viewed...

Species: Hu
Applications: BA
Species: Hu, Mu
Applications: Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
Species: Hu
Applications: CyTOF-ready, ELISA, Flow, ICC/IF, IHC, IHC-P, PA, WB
Species: Hu
Applications: CyTOF-ready, Flow, Neut, WB
Species: Hu
Applications: B/N, CyTOF-ready, ELISA, Flow-CS, Flow, ICC/IF, IHC, IHC-Fr, Simple Western
Species: Hu
Applications: Block, CyTOF-ready, Flow
Species: Hu
Applications: CyTOF-ready, Flow
Species: Rt
Applications: B/N, CyTOF-ready, EM, ELISA, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Species: Hu
Applications: Block, CyTOF-reported, Flow
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, WB
Species: Hu, Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, IP, WB
Species: Hu
Applications: CyTOF-ready, Flow, WB
Species: Hu
Applications: WB
Species: Mu
Applications: ELISA
Species: Mu, Rt
Applications: Cell Depl, CyTOF-ready, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, InhibTFunc
Species: Hu
Applications: AgAct, CyTOF-reported, Flow
Species: Hu
Applications: BA
Species: Hu
Applications: CostimT, CyTOF-ready, Flow, Neut, WB
Species: Rt
Applications: Bioactivity

Publications for LILRC2 (9808-T4) (0)

There are no publications for LILRC2 (9808-T4).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for LILRC2 (9808-T4) (0)

There are no reviews for LILRC2 (9808-T4). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

FAQs for LILRC2 (9808-T4) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Customers Who Bought This Also Bought

Contact Information

Product PDFs


Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.


Review this Product

Be the first to review our Recombinant Rat LILRC2 Protein, CF and receive a gift card or discount.