LILRC2 (leukocyte immunoglobulin-like receptor C2) is a 35 kDa member of a family of inhibitory and stimulatory receptors (LILRs) that are expressed on hematopoietic cells. Mature rat LILRC2 is a type I transmembrane (TM) protein that is 241 amino acids (aa) in length. It contains a 207 aa extracellular domain (ECD), a 19 aa TM segment, and a short cytoplasmic tail. The ECD contains two Ig-like domains while the TM segment possesses an Arg residue. This suggests that LILRC2 is an activating receptor that may interact with Fc epsilon RI gamma and/or CD3 zeta . Cells expressing LILRC2 include neutrophils, B cells, and CD4+ and CD8+ T cells. No human or mouse LILRC2 is known.
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| Product By Gene ID | 10859 |
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![Binding Activity LILRC2 [Unconjugated]](http://images.novusbio.com/fullsize2/LILRC2_9808T4_1924.jpg)