RECK Antibody (198212) [PerCP]

• Reactivity: Hu
• Applications: WB, IP
• Clone: 198212
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: PerCP

RECK Antibody (198212) [PerCP] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human RECK
  Ala29-Val934
  Accession # O95980
• Specificity: Detects human RECK in direct ELISAs and Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: RECK
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for RECK Antibody (198212) [PerCP]

• hRECK
• membrane-anchored glycoprotein (metastasis and invasion)
• RECK
• reversion-inducing-cysteine-rich protein with kazal motifs
• ST15
• ST15reversion-inducing cysteine-rich protein with Kazal motifs
• suppression of tumorigenicity 15 (reversion-inducing-cysteine-rich protein withkazal motifs)
• suppression of tumorigenicity 5 (reversion-inducing-cysteine-rich protein withkazal motifs)
• Suppressor of tumorigenicity 15 protein

Background

RECK is encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RECK