RCOR1/CoREST Antibody [Allophycocyanin]

• Reactivity: Hu, Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Allophycocyanin

RCOR1/CoREST Antibody [Allophycocyanin] Summary

• Immunogen: E. coli-derived recombinant human RCOR1/CoREST
  Ala397-Ser486
  Accession # Q9UKL0
• Specificity: Detects human and mouse RCOR1/CoREST in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: RCOR1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for RCOR1/CoREST Antibody [Allophycocyanin]

• CoREST
• KIAA0071CORESTRCORREST corepressor
• Protein CoREST
• RCOR1
• RCOR1/CoREST
• REST corepressor 1

Background

Brain type II sodium channels are important in neuronal phenotyping and are only seen at high levels in neurons. Studies have shown that CoREST functions as a corepressor for REST. This interaction between REST and CoREST is accomplished by means of a single zinc finger binding motif originating from REST. Together, the REST-CoREST complex mediates long term repression of the type II sodium channel gene (1).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RCOR1