Rat C-Reactive Protein/CRP DuoSet ELISA, 15 Plate

• Reactivity: Rt
• Applications: ELISA
• Conjugate: Biotin

Rat C-Reactive Protein/CRP DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Crp

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Rat C-Reactive Protein/CRP DuoSet ELISA, 15 Plate

• C-Reactive Protein
• C-reactive protein, pentraxin-related
• CRP
• MGC88244
• pentraxin 1
• PTX1MGC149895

Background

C-Reactive Protein (CRP), also known as Pentraxin 1, is a secreted pentameric protein that functions as a sensor and activator for the innate immune response. In humans, it is a major acute-phase protein; its circulating concentration is dramatically elevated at the onset of inflammation. In mice, however, serum CRP levels increase only slightly during inflammation, and the analogous acute phase role is filled by Pentraxin 2. CRP binds, opsonizes, and induces the phagocytosis of bacteria and apoptotic cells. It regulates activation of the classical complement pathway by binding several proteins in the complement cascade as well as Fc gamma RI, Fc gamma RIIA, and Fc gamma RIIB on macrophages and dendritic cells. It also promotes dendritic cell maturation and humoral immunity. In cardiovascular disease, CRP binds to oxidized LDL, exacerbates tissue damage in myocardial infarction, and inhibits the repair of injured vascular endothelium.

Publications for C-Reactive Protein/CRP (DY1744)(13)

Publications using DY1744

• Gagné, MA;Frégeau, G;Godbout, R;Rousseau, G; The Role of Probiotics in Modulating Myocardial Infarction and Depression-like Symptoms: A Study on Sex-Specific Responses Biomedicines 2024-11-02 [PMID: 39595077] (Rat)
• Ergin, B;Kutucu, DE;Kapucu, A;van Dam, W;Moretto, L;Heyman, P;Ince, C; Hemoadsorption improves kidney microcirculatory oxygenation and oxygen consumption, ameliorates tubular injury, and improves kidney function in a rat model of sepsis-induced AKI Scientific reports 2024-11-18 [PMID: 39558075] (Rat)
• IA Alsharif, HM Fayed, RF Abdel-Rahm, RM Abd-Elsala, HA Ogaly Miconazole Mitigates Acetic Acid-Induced Experimental Colitis in Rats: Insight into Inflammation, Oxidative Stress and Keap1/Nrf-2 Signaling Crosstalk Biology, 2022-02-13;11(2):. 2022-02-13 [PMID: 35205169] (Rat)
• L Zizmare, CN Boyle, S Buss, S Louis, L Kuebler, K Mulay, R Krüger, L Steinhauer, I Mack, M Rodriguez, K Herfert, Y Ritze, C Trautwein Roux-En-Y Gastric Bypass (RYGB) Surgery during High Liquid Sucrose Diet Leads to Gut Microbiota-Related Systematic Alterations International Journal of Molecular Sciences, 2022-01-20;23(3):. 2022-01-20 [PMID: 35163046] (Rat)
• RVP Neves, HL Corrêa, IV de Sousa N, MK Souza, F Costa, AS Haro, LA Deus, AL Reis, HG Simões, RV Andrade, CO Assumpção, W Stone, J Prestes, EC Vieira, R de Cássia, V Cruzat, TS Rosa Renoprotection Induced by Aerobic Training Is Dependent on Nitric Oxide Bioavailability in Obese Zucker Rats Oxidative Medicine and Cellular Longevity, 2021-09-28;2021(0):3683796. 2021-09-28 [PMID: 34621463] (Rat)
• L Liu, R Hu, H You, J Li, Y Liu, Q Li, X Wu, J Huang, X Cai, M Wang, L Wei Formononetin ameliorates muscle atrophy by regulating myostatin-mediated PI3K/Akt/FoxO3a pathway and satellite cell function in chronic kidney disease Journal of Cellular and Molecular Medicine, 2021-01-06;0(0):. 2021-01-06 [PMID: 33405354] (Rat)
• DY Seo, JH Bae, TN Kim, HB Kwak, PT Kha, J Han Exercise-Induced Circulating Irisin Level Is Correlated with Improved Cardiac Function in Rats Int J Environ Res Public Health, 2020-05-29;17(11):. 2020-05-29 [PMID: 32485990] (Rat)
• ZH Yang, YJ Lu, KP Gu, ZY Xiang, HM Huang Effect of ulinastatin on myocardial ischemia-reperfusion injury through JNK and P38 MAPK signaling pathways Eur Rev Med Pharmacol Sci, 2019-10-01;23(19):8658-8664. 2019-10-01 [PMID: 31646600] (Rat)
• M Wang, R Hu, Y Wang, L Liu, H You, J Zhang, X Wu, T Pei, F Wang, L Lu, W Xiao, L Wei Atractylenolide III Attenuates Muscle Wasting in Chronic Kidney Disease via the Oxidative Stress-Mediated PI3K/AKT/mTOR Pathway Oxid Med Cell Longev, 2019-04-18;2019(0):1875471. 2019-04-18 [PMID: 31178951] (Rat)
• X Wei, J Tao, S Xiao, S Jiang, E Shang, Z Zhu, D Qian, J Duan Xiexin Tang improves the symptom of type 2 diabetic rats by modulation of the gut microbiota Sci Rep, 2018-02-27;8(1):3685. 2018-02-27 [PMID: 29487347] (Rat)
• X Wang Role of methotrexate chronotherapy in collagen-induced rheumatoid arthritis in�rats Z Rheumatol, 2018-04-01;0(0):. 2018-04-01 [PMID: 27900440] (Rat)
• Miyajima S, Naruse K, Kobayashi Y, Nakamura N, Nishikawa T, Adachi K, Suzuki Y, Kikuchi T, Mitani A, Mizutani M, Ohno N, Noguchi T, Matsubara T Periodontitis-activated monocytes/macrophages cause aortic inflammation. Sci Rep, 2014-06-04;4(0):5171. 2014-06-04 [PMID: 24893991] (Rat)
• Wang Y, Chen C, Lin S, Chuang Y, Sheu W, Tung K Hyperglycemia is associated with enhanced gluconeogenesis in a rat model of permanent cerebral ischemia. Mol Cell Endocrinol, 2012-12-29;367(1):50-6. 2012-12-29 [PMID: 23279876] (Rat)

Bioinformatics

• Gene Symbol: Crp