RARRES3 Antibody (659209) [Alexa Fluor® 700]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 659209
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 700

RARRES3 Antibody (659209) [Alexa Fluor® 700] Summary

• Immunogen: E. coli-derived recombinant human RARRES3
  Asp12-Lys134
  Accession # Q9UL19
• Specificity: Recognizes human RARRES3 in Western blots and direct ELISAs. In Western blots and direct ELISAs, no cross-reactivity with recombinant human (rh) RARRES1 or rhLatexin is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for RARRES3 Antibody (659209) [Alexa Fluor® 700]

• HRASLS4
• PLA1/2-3
• RARRES3
• RAR-responsive protein TIG3
• retinoic acid receptor responder (tazarotene induced) 3
• retinoic acid receptor responder protein 3
• retinoic acid-inducible gene 1
• Retinoid-inducible gene 1 protein
• RIG1
• Tazarotene-induced gene 3 protein
• TIG3
• TIG3MGC8906

Background

RARRES3 (retinoic acid receptor responder 3), also called Tig3 (tazarotene-induced gene 3) or RIG1 (retinoid-inducible gene 1), is an 18 kDa, 164 amino acid (aa) cytoplasmic protein within the LRAT (lecithin retinol acyltransferase) family of growth inhibitory proteins, which are class II tumor-suppressors. RARRES3 is expressed in a variety of cells including epidermal keratinocytes, and may be downregulated in tumor cells and cell lines. It shows phospholipase activity and interaction with type I transglutaminase. A C-terminal hydrophobic region allows perinuclear localization. RARRES3 is not structurally related to other RARRES genes. A canine ortholog shares 72% aa identity within the region used as an immunogen; orthologs are unlikely in rodents.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.