Independent Antibodies: Western Blot: RAP6 Antibody [NBP1-19156] - Whole cell lysate from HeLa cells. GAPex5 was also immunoprecipitated by rabbit anti-GAPex5 antibody NBP1-19157.
Novus Biologicals Rabbit RAP6 Antibody (NBP1-19156) is a polyclonal antibody validated for use in WB and IP. Anti-RAP6 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
The immunogen recognized by this antibody maps to a region between residue 550 and 600 of human GTPase activating protein and VPS9 domains 1 using the numbering given in entry BAG10470.1 (GeneID 26130).
Predicted Species
Mouse (100%), Xenopus (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GAPVD1
Purity
Immunogen affinity purified
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GTPase-activating protein and VPS9 domain-containing protein 1
KIAA1521MGC138848
MGC138847
Background
GAPex-5 was identified in a two-hybrid screen for interactors of CIP4 (Cdc42 interacting protein 4). GAPex-5 contains a Ras-GAP domain and a VPS9 (vacuolar sorting protein 9 (VPS9) domain. It functions as a GEF for RAB31 to influence GLUT4 trafficking. It has also been found to be involved in the trafficking and ubiquitination of EGFR. Alternate names for GAPex-5 include GTPase-activating protein and VPS9 domain-containing protein 1, Rab5-activating protein 6, GAPVD1, GAPEX5, RAP6, and KIAA1521.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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