RANBP9 Antibody

Product Discontinued

RANBP9 Antibody Summary

• Immunogen: Peptide with sequence GSCAFATVEDYLH corresponding to C-Terminus according to NP_005484.2.
• Specificity: This product is also expected to recognize the centrosome-associated truncated isoform RANBPM (BAA23216.1).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: RANBP9
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 3 - 10 ug/mL
  • Immunohistochemistry-Paraffin 3 - 10 ug/mL
  • Peptide ELISA Detection limit 1:16000
• Application Notes: ICC: A customer reported successful use on HeLa. WB: Preliminary experiments gave no signal but low background in whole cell Hela lysates at up to 1 ug/ml. IHC-P: Human tonsil stains nuclei in epithelial cells of tonsillar criptae.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Canine, Porcine.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for RANBP9 Antibody

• BPM90
• BPM-L
• RAN binding protein 9
• Ran Binding Protein in the Microtubule organizing center
• ran binding protein, centrosomal
• ran-binding protein 9
• Ran-binding protein M
• RanBP7
• RanBP9
• RanBPM
• RANBPMnovel centrosomal protein RanBPM

Background

This gene encodes a 55-kD protein of 500 amino acid residues which is localized within the centrosome throughout the cell cycle. Mouse, hamster, and human forms of this protein are identical. This protein is localized within the central part of microtubule asters and is involved in microtubule nucleation and regulation of the centrosome by RAN.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for RANBP9 Antibody (NB100-1281)(2)

Publications using NB100-1281

• Gong X, Ye W, Zhou H et al. RanBPM is an acetylcholinesterase-interacting protein that translocates into the nucleus during apoptosis. RanBPM is an acetylcholinesterase-interacting protein that translocates into the nucleus during apoptosis. [PMID: 19902122]
• Wang D, Li Z, Messing EM, Wu G. Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM. J Biol Chem 2002-09-27 [PMID: 12147692]

Bioinformatics

• Gene Symbol: RANBP9
• Entrez:
  • 10048(Human)
  • 56705(Mouse)
• Uniprot:
  • NP_005484.(Human)