Rab13 Antibody (863028) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB, ICC/IF, KO
• Clone: 863028
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

Rab13 Antibody (863028) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human Rab13
  Lys94-Thr191
  Accession # P51153
• Specificity: Detects human Rab13 in direct ELISA and Western Blot.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Knockout Validated
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Rab13 Antibody (863028) [Alexa Fluor® 488]

• Cell growth-inhibiting gene 4 protein
• growth-inhibiting gene 4 protein
• Rab13
• RAB13, member RAS oncogene family
• RAS-associated protein RAB13
• ras-related protein Rab-13

Background

Ras-related protein Rab13 is a 23 kDa member of the Rab family of small GTPases.  With more than 40 family members, Rab proteins are regulators of vesicular transport, and their number reflects the complexity of vesicle trafficking.  Rab13 is detected in endothelial cells and a variety of epithelia, including intestine, lung, kidney and liver.  Rab13 may participate in the assembly and activity of tight junctions, as it colocalizes with the marker ZO-1 in polarized epithelial cells.  In addition, insulin promotes GTP loading of Rab13, potentially regulating GLUT4 translocation in skeletal muscle cells.  Human Rab13 is 203 amino acids (aa) in length, with residues 201-203 removed in its mature form.  Over aa 94-191, human Rab13 shares 89 and 90% identity with mouse and rat Rab13, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.