PTP gamma/PTPRG Antibody (481505) [mFluor Violet 610 SE]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: 481505
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 610 SE

PTP gamma/PTPRG Antibody (481505) [mFluor Violet 610 SE] Summary

• Immunogen: E. coli-derived recombinant human PTP gamma /PTPRG
  Ser111-Ala541
  Accession # P23470
• Specificity: Detects human, mouse, and rat PTP gamma /PTPRG in Western blots. In Western blots, no cross-reactivity with recombinant human PTPRM, PTPRK, PTPRS, LAR, or DEP1 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: PTPRG
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PTP gamma/PTPRG Antibody (481505) [mFluor Violet 610 SE]

• EC 3.1.3.48
• H_RG317H01.1
• HPTPG
• protein tyrosine phosphatase, receptor type, G
• protein tyrosine phosphatase, receptor type, gamma polypeptide
• Protein-tyrosine phosphatase gamma
• PTP gamma
• PTPG
• PTPGprotein tyrosine phosphatase gamma
• PTPRG
• receptor type protein tyrosine phosphatase gamma
• receptor tyrosine phosphatase gamma
• receptor-type protein phosphatase gamma
• receptor-type tyrosine-protein phosphatase gamma
• RPTPG
• R-PTP-GAMMA

Background

PTPRG is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTPRG