PTP gamma/PTPRG Antibody (481505) [Alexa Fluor® 350]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: 481505
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 350

PTP gamma/PTPRG Antibody (481505) [Alexa Fluor® 350] Summary

• Immunogen: E. coli-derived recombinant human PTPγ/PTPRG
  Ser111-Ala541
  Accession # P23470
• Specificity: Detects human, mouse, and rat PTP gamma /PTPRG in Western blots. In Western blots, no cross-reactivity with recombinant human PTPRM, PTPRK, PTPRS, LAR, or DEP1 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PTP gamma/PTPRG Antibody (481505) [Alexa Fluor® 350]

• EC 3.1.3.48
• H_RG317H01.1
• HPTPG
• protein tyrosine phosphatase, receptor type, G
• protein tyrosine phosphatase, receptor type, gamma polypeptide
• Protein-tyrosine phosphatase gamma
• PTP gamma
• PTPG
• PTPGprotein tyrosine phosphatase gamma
• PTPRG
• receptor type protein tyrosine phosphatase gamma
• receptor tyrosine phosphatase gamma
• receptor-type protein phosphatase gamma
• receptor-type tyrosine-protein phosphatase gamma
• RPTPG
• R-PTP-GAMMA

Background

Protein Tyrosine Phosphatase, Receptor type gamma (PTPR gamma ), also called PTPRG and PTPG, is a transmembrane protein. Its extracellular region contains carbonic anhydrase fibronectin III domains, suggesting that it interacts with adhesion molecules, but the only reported activator is an intracellular ATP-dependent factor. During brain development, PTPR gamma is found exclusively in post-mitotic neurons. A wide variety of cancers, including colon, renal clear cell, lung, breast, and cervical cancers, show a high incidence of defects in the PTPR gamma gene, suggesting the protein has a key regulatory function in tumor suppression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.