PTP gamma/PTPRG Antibody (481505)

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Western blot shows lysates of CHP‑100 human neuroblastoma cell line, SH‑SY5Y human neuroblastoma cell line, and Neuro‑2A mouse neuroblastoma cell line. PVDF membrane was probed with 1 µg/mL of Mouse ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clone
481505
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price

PTP gamma/PTPRG Antibody (481505) Summary

Immunogen
E. coli-derived recombinant human PTP gamma /PTPRG
Ser111-Ala541
Accession # P23470
Specificity
Detects human, mouse, and rat PTP gamma /PTPRG in Western blots. In Western blots, no cross-reactivity with recombinant human PTPRM, PTPRK, PTPRS, LAR, or DEP1 is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PTPRG
Purity
Protein A or G purified from hybridoma culture supernatant
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
Publications
Read Publications using
MAB4608 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PTP gamma/PTPRG Antibody (481505)

  • EC 3.1.3.48
  • H_RG317H01.1
  • HPTPG
  • protein tyrosine phosphatase, receptor type, G
  • protein tyrosine phosphatase, receptor type, gamma polypeptide
  • Protein-tyrosine phosphatase gamma
  • PTP gamma
  • PTPG
  • PTPGprotein tyrosine phosphatase gamma
  • PTPRG
  • receptor type protein tyrosine phosphatase gamma
  • receptor tyrosine phosphatase gamma
  • receptor-type protein phosphatase gamma
  • receptor-type tyrosine-protein phosphatase gamma
  • RPTPG
  • R-PTP-GAMMA

Background

Protein Tyrosine Phosphatase, Receptor type gamma (PTPR gamma ), also called PTPRG and PTPG, is a transmembrane protein. Its extracellular region contains carbonic anhydrase fibronectin III domains, suggesting that it interacts with adhesion molecules, but the only reported activator is an intracellular ATP-dependent factor. During brain development, PTPR gamma is found exclusively in post-mitotic neurons. A wide variety of cancers, including colon, renal clear cell, lung, breast, and cervical cancers, show a high incidence of defects in the PTPR gamma gene, suggesting the protein has a key regulatory function in tumor suppression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PTP gamma/PTPRG Antibody (MAB4608)(2)

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Secondary Antibodies

 

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Diseases for PTP gamma/PTPRG Antibody (MAB4608)

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Bioinformatics

Gene Symbol PTPRG
Uniprot