PSMA/FOLH1/NAALADase I Antibody - BSA Free

Analysis in human prostate and pancreas tissues using NBP1-89822 antibody. Corresponding FOLH1 RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: PSMA/FOLH1/NAALADase I Antibody [NBP1-89822] - Staining of human prostate shows strong positivity in apical membrane in glandular cells.

Staining of human pancreas shows no positivity in exocrine glandular cells as expected.

Immunohistochemistry-Paraffin: PSMA/FOLH1/NAALADase I Antibody [NBP1-89822] - Staining of human duodenum shows moderate positivity in apical membrane in glandular cells.

Immunohistochemistry-Paraffin: PSMA/FOLH1/NAALADase I Antibody [NBP1-89822] - Staining of human placenta shows no positivity in trophoblastic cells as expected.

• Reactivity: Hu, Rt
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PSMA/FOLH1/NAALADase I Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PSMA/FOLH1/NAALADase I Antibody - BSA Free (NBP1-89822) is a polyclonal antibody validated for use in IHC. Anti-PSMA/FOLH1/NAALADase I Antibody: Cited in 3 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: ADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNF
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FOLH1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
• Application Notes: Retrieval method: HIER pH6
• Control Peptide:

  PSMA/FOLH1/NAALADase I Protein (NBP1-89822PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%) Use in Rat reported in scientific publication (PMID: 32451793).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for PSMA/FOLH1/NAALADase I Antibody - BSA Free

• Cell growth-inhibiting gene 27 protein
• cell growth-inhibiting protein 27
• EC 3.4.17.21
• FGCP
• folate hydrolase (prostate-specific membrane antigen) 1
• Folate hydrolase 1
• FOLH1
• FOLHNAALADase I
• Folylpoly-gamma-glutamate carboxypeptidase
• GCP2
• GCPII
• GCPIImGCP
• glutamate carboxylase II
• glutamate carboxypeptidase 2
• Glutamate carboxypeptidase II
• Membrane glutamate carboxypeptidase
• mopsm
• NAALAD1
• NAALAD1N-acetylated-alpha-linked acidic dipeptidase I
• NAALADase I
• NAALAdase
• N-acetylated alpha-linked acidic dipeptidase 1
• prostate specific membrane antigen variant F
• Prostate-specific membrane antigen
• PSMA
• PSMAFGCP
• PSMPteroylpoly-gamma-glutamate carboxypeptidase

Background

PSMA, also known as Glutamate carboxypeptidase 2, is a 84kDa 750 amino acid protein that has 8 isoforms produced by alternative splicing. The primary function of this protein is to act as a glutamate carboxypeptidase. Current research on PSMA is being conducted in relation to prostate cancer, muscular atrophy, small cell carcinoma, coronary heart disease and Huntington's disease. PSMA is known to interact with MME, MTAP and RPS3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PSMA/FOLH1/NAALADase I Antibody (NBP1-89822)(3)

Publications using NBP1-89822

• Oliveira D, Stegmayr C, Heinzel A et al. High uptake of 68Ga-PSMA and 18F-DCFPyL in the peritumoral area of rat gliomas due to activated astrocytes EJNMMI Res 2020-05-25 [PMID: 32451793] (IF/IHC, Rat)
• Hudson EP, Uhlen M, Rockberg J. Multiplex epitope mapping using bacterial surface display reveals both linear and conformational epitopes. Sci Rep 2012-01-01 [PMID: 23050090]
• Jaraj SJ, Augsten M, Haggarth L et al. GAD1 is a biomarker for benign and malignant prostatic tissue. Scand J Urol Nephrol 2011-02-01 [PMID: 21091088]

Bioinformatics

• Gene Symbol: FOLH1
• Entrez:
  • 2346(Human)
• Uniprot:
  • Q04609()