Protein Phosphatase 1C gamma Antibody - BSA Free

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB
• Clonality: Polyclonal
• Host: Chicken
• Conjugate: Unconjugated
• Format: BSA Free

Protein Phosphatase 1C gamma Antibody - BSA Free Summary

• Description: Novus Biologicals Chicken Protein Phosphatase 1C gamma Antibody - BSA Free (NB100-75543) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen for this antibody was a sequence from 1a.a. to 323a.a. from PP1C(a 323a.a. long protein)
• Localization: Cytoplasmic
• Specificity: Protein Phosphatase 1C gamma
• Clonality: Polyclonal
• Host: Chicken
• Gene: PPP1CC
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Western Blot: E coli-derived recombinant protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
• Control:

  Protein Phosphatase 1C gamma Overexpression Lysate

Reactivity Notes

This antibody is reactive against Human, mouse, rat, bovine.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Chicken products cannot be exported to Canada.

Alternate Names for Protein Phosphatase 1C gamma Antibody - BSA Free

• EC 3.1.3.16
• PP-1G
• PP1gamma
• PPP1G
• protein phosphatase 1, catalytic subunit, gamma isoform
• protein phosphatase 1, catalytic subunit, gamma isozyme
• Protein phosphatase 1C catalytic subunit
• serine/threonine phosphatase 1 gamma
• serine/threonine-protein phosphatase PP1-gamma catalytic subunit

Background

Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. The protein is involved in regulation of ionic conductances and long term synaptic plasticity. It may play an important role in dephosphorylating substrates such as the postsynaptic density associated Ca (2+)/calmodulin dependent protein kinase II. PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC (PP1C gamma), which is folded into its native form by inhibitor 2 and glycogen synthetase kinase 3, and then complexed to one or several targeting or regulatory subunits. PPP1R12A and PPP1R12B mediate binding to myosin. PPP1R3A, PPP1R3B, PPP1R3C and PPP1R3D mediate binding to glycogen. Interacts with cyanobacterial toxin microcystin; disulfide-linked. Interacts with PPP1R7.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PPP1CC
• Entrez:
  • 5501(Human)
  • 19047(Mouse)
  • 24669(Rat)
• Uniprot:
  • P36873(Human)