Proteasome beta 1 Antibody - BSA Free

Immunohistochemistry: Proteasome beta 1 Antibody - BSA Free [NBP3-46865] - Immunohistochemistry of paraffin-embedded human esophageal cancer using (Proteasome beta 1 antibody) at dilution of 1:50

Western Blot: Proteasome beta 1 Antibody - BSA Free [NBP3-46865] - HeLa cells were subjected to SDS PAGE followed by western blot with (Proteasome beta 1 antibody) at dilution of 1:1000

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Proteasome beta 1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Proteasome beta 1 Antibody - BSA Free (NBP3-46865) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: proteasome (prosome, macropain) subunit, beta type, 1. (Uniprot# P20618)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PSMB1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 1:50 - 1:200
  • Immunohistochemistry 1:50 - 1:200
  • Western Blot 1:500 - 1:2000
• Theoretical MW: 23 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Proteasome beta 1 Antibody - BSA Free

• EC 3.4.25.1
• FLJ25321
• HC5
• KIAA1838
• Macropain subunit C5
• Multicatalytic endopeptidase complex subunit C5
• PMSB1
• proteasome (prosome, macropain) subunit, beta type, 1
• proteasome beta 1 subunit
• Proteasome beta 1
• Proteasome component C5
• Proteasome gamma chain
• proteasome subunit beta type-1
• proteasome subunit HC5
• PSC5
• PSMB1

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PSMB1