Proteasome beta 1 Products

Description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. [provided by RefSeq]

Bioinformatics

Entrez	5689 Human
Uniprot	NM_002793 Human NP_002784 Human NP_002784.1 Human P20618 Human
Product By Gene ID	5689
Alternate Names	EC 3.4.25.1 FLJ25321 HC5 KIAA1838 Macropain subunit C5 Multicatalytic endopeptidase complex subunit C5 PMSB1 proteasome (prosome, macropain) subunit, beta type, 1 proteasome beta 1 subunit Proteasome component C5 Proteasome gamma chain proteasome subunit beta type-1 proteasome subunit HC5 PSC5