Proteasome 20S beta 6 Antibody - BSA Free

Immunohistochemistry: Proteasome 20S beta 6 Antibody [NBP3-14763] - Immunochemical staining of human Proteasome 20S beta 6 in human liver with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.

Immunohistochemistry: Proteasome 20S beta 6 Antibody [NBP3-14763] - Immunochemical staining of human Proteasome 20S beta 6 in human kidney with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Proteasome 20S beta 6 Antibody - BSA Free Summary

• Description: This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Immunogen: Produced in rabbits immunized with E. coli-derived Human Proteasome 20S beta 6 fragment
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PSMB6
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 1:100-1:500

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.03% Proclin 300
• Purity: Antigen and protein A Affinity-purified

Alternate Names for Proteasome 20S beta 6 Antibody - BSA Free

• DELTA
• EC 3.4.25.1
• LMPY
• Macropain delta chain
• Multicatalytic endopeptidase complex delta chain
• proteasome (prosome, macropain) subunit, beta type, 6
• Proteasome 20S beta 6
• proteasome catalytic subunit 1
• Proteasome delta chain
• proteasome subunit beta 6
• proteasome subunit beta type-6
• proteasome subunit delta
• Proteasome subunit Y
• PSMB6
• PSY large multifunctional protease Y
• YMGC5169

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 1i (proteasome beta 9 subunit).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PSMB6